PDB entry 4lkx

View 4lkx on RCSB PDB site
Description: humanized antibody 4b12 fab complexed with a cemx segment
Deposited on 2013-07-09, released 2014-01-29
The last revision was dated 2015-06-17, with a file datestamp of 2015-06-12.
Experiment type: XRAY
Resolution: 1.92 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fab fragment heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4LKX (0-End)
  • Chain 'B':
    Compound: Fab fragment light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4LKX (0-218)
  • Chain 'R':
    Compound: CemX segment
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4LKX (0-13)
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4lkxA (A:)
qvqlqesgpglvkpsetlsltctvsgysitsdyawnwirqppgkglewigsisysgitgy
npslksrvtisrdtsknqfslklssvtaadtavyycarmgydglaywgqgtlvtvssast
kgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgly
slssvvtvpssslgtqtyicnvnhkpsntkvdkkaepkscdktht

    Sequence, based on observed residues (ATOM records):
    >4lkxA (A:)
qvqlqesgpglvkpsetlsltctvsgysitsdyawnwirqppgkglewigsisysgitgy
npslksrvtisrdtsknqfslklssvtaadtavyycarmgydglaywgqgtlvtvssast
kgpsvfplapsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssv
vtvpssslgtqtyicnvnhkpsntkvdkkaepks

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records:
    >4lkxB (B:)
divmtqtplslsvtpgqpasiscrssqsivhsngntylewylqkpgqspqlliykvsnrf
sgvpdrfsgsgsgtdftlkisrveaedvgvyycfqgshvpptfgggtkveikrtvaapsv
fifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysl
sstltlskadyekhkvyacevthqglsspvtksfnrgec

  • Chain 'R':
    Sequence; same for both SEQRES and ATOM records:
    >4lkxR (R:)
laggsaqsqrapdr