PDB entry 4lgg

View 4lgg on RCSB PDB site
Description: Structure of 3MB-PP1 bound to analog-sensitive Src kinase
Class: transferase/transferase inhibitor
Keywords: Kinase Domain, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2013-06-27, released 2013-08-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 2.41 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Proto-oncogene tyrosine-protein kinase Src
    Species: Gallus gallus [TaxId:9031]
    Gene: SRC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00523 (0-269)
      • engineered mutation (74)
    Domains in SCOPe 2.08: d4lgga_
  • Chain 'B':
    Compound: Proto-oncogene tyrosine-protein kinase Src
    Species: Gallus gallus [TaxId:9031]
    Gene: SRC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00523 (0-269)
      • engineered mutation (74)
    Domains in SCOPe 2.08: d4lggb_
  • Heterogens: VGG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4lggA (A:)
reslrlevklgqgcfgevwmgtwngttrvaiktlkpgtmspeaflqeaqvmkklrheklv
qlyavvseepiyivgeymskgslldflkgemgkylrlpqlvdmaaqiasgmayvermnyv
hrdlraanilvgenlvckvadfglarliedneytarqgakfpikwtapeaalygrftiks
dvwsfgilltelttkgrvpypgmvnrevldqvergyrmpcppecpeslhdlmcqcwrkdp
eerptfeylqafledyftstepqyqpgenl

    Sequence, based on observed residues (ATOM records): (download) 
    >4lggA (A:)
reslrlevklgqggevwmgtwngttrvaiktlkpglqeaqvmkklrheklvqlyavvsee
iyivgeymskgslldflkgemgkylrlpqlvdmaaqiasgmayvermnyvhrdlraanil
vgenlvckvadfpikwtapeaalygrftiksdvwsfgilltelttkgrvpypgmvnrevl
dqvergyrmpcppecpeslhdlmcqcwrkdpeerptfeylqafledyftstepqyqpgen
l

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4lggB (B:)
reslrlevklgqgcfgevwmgtwngttrvaiktlkpgtmspeaflqeaqvmkklrheklv
qlyavvseepiyivgeymskgslldflkgemgkylrlpqlvdmaaqiasgmayvermnyv
hrdlraanilvgenlvckvadfglarliedneytarqgakfpikwtapeaalygrftiks
dvwsfgilltelttkgrvpypgmvnrevldqvergyrmpcppecpeslhdlmcqcwrkdp
eerptfeylqafledyftstepqyqpgenl

    Sequence, based on observed residues (ATOM records): (download) 
    >4lggB (B:)
reslrlevklggevwmgtwngttrvaiktlkpgtmspeaflqeaqvmkklrheklvqlya
vvseeyivgeymskgslldflkgemgkylrlpqlvdmaaqiasgmayvermnyvhrdlra
anilvgenlvckvadfpikwtapeaalygrftiksdvwsfgilltelttkgrvpypgmvn
revldqvergyrmpcppecpeslhdlmcqcwrkdpeerptfeylqafledyftstepqyq
pgenl