PDB entry 4ley

View 4ley on RCSB PDB site
Description: Structure of mouse cGAS bound to 18 bp DNA
Deposited on 2013-06-26, released 2013-12-25
The last revision was dated 2014-01-08, with a file datestamp of 2014-01-03.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.161
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cyclic GMP-AMP synthase
    Species: Mus musculus [TaxId:10090]
    Gene: Mb21d1
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Cyclic GMP-AMP synthase
    Species: Mus musculus [TaxId:10090]
    Gene: Mb21d1
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Cyclic GMP-AMP synthase
    Species: Mus musculus [TaxId:10090]
    Gene: Mb21d1
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Cyclic GMP-AMP synthase
    Species: Mus musculus [TaxId:10090]
    Gene: Mb21d1
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: 18 bp dsDNA
    Species: synthetic, synthetic
  • Chain 'F':
    Compound: 18 bp dsDNA
    Species: synthetic, synthetic
  • Chain 'G':
    Compound: 18 bp dsDNA
    Species: synthetic, synthetic
  • Chain 'H':
    Compound: 18 bp dsDNA
    Species: synthetic, synthetic
  • Chain 'I':
    Compound: 18 bp dsDNA
    Species: synthetic, synthetic
  • Chain 'J':
    Compound: 18 bp dsDNA
    Species: synthetic, synthetic
  • Chain 'K':
    Compound: 18 bp dsDNA
    Species: synthetic, synthetic
  • Chain 'L':
    Compound: 18 bp dsDNA
    Species: synthetic, synthetic
  • Heterogens: ZN, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4leyA (A:)
gsrkepdklkkvldklrlkrkdiseaaetvnkvverllrrmqkresefkgveqlntgsyy
ehvkisapnefdvmfklevprielqeyyetgafylvkfkriprgnplshflegevlsatk
mlskfrkiikeevkeikdidvsvekekpgspavtllirnpeeisvdiilaleskgswpis
tkeglpiqgwlgtkvrtnlrrepfylvpknakdgnsfqgetwrlsfshtekyilnnhgie
ktccessgakccrkeclklmkylleqlkkefqeldafcsyhvktaifhmwtqdpqdsqwd
prnlsscfdkllaffleclrtekldhyfipkfnlfsqelidrkskeflskkieyernngf
pifdkl

    Sequence, based on observed residues (ATOM records):
    >4leyA (A:)
klkkvldklrlkrkdiseaaetvnkvverllrrmqkresefkgveqlntgsyyehvkisa
pnefdvmfklevprielqeyyetgafylvkfkriprgnplshflegevlsatkmlskfrk
iikeevkeikdidvsvekekpgspavtllirnpeeisvdiilaleskgswpistkeglpi
qgwlgtkvrtnlrrepfylvpknakdgnsfqgetwrlsfshtekyilnnhgiektccess
gakccrkeclklmkylleqlkkefqeldafcsyhvktaifhmwtqdpqdsqwdprnlssc
fdkllaffleclrtekldhyfipkfnlfsqelidrkskeflskkieyernngfpifdkl

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4leyB (B:)
gsrkepdklkkvldklrlkrkdiseaaetvnkvverllrrmqkresefkgveqlntgsyy
ehvkisapnefdvmfklevprielqeyyetgafylvkfkriprgnplshflegevlsatk
mlskfrkiikeevkeikdidvsvekekpgspavtllirnpeeisvdiilaleskgswpis
tkeglpiqgwlgtkvrtnlrrepfylvpknakdgnsfqgetwrlsfshtekyilnnhgie
ktccessgakccrkeclklmkylleqlkkefqeldafcsyhvktaifhmwtqdpqdsqwd
prnlsscfdkllaffleclrtekldhyfipkfnlfsqelidrkskeflskkieyernngf
pifdkl

    Sequence, based on observed residues (ATOM records):
    >4leyB (B:)
klkkvldklrlkrkdiseaaetvnkvverllrrmqkresefkgveqlntgsyyehvkisa
pnefdvmfklevprielqeyyetgafylvkfkriprgnplshflegevlsatkmlskfrk
iikeevkeikdidvsvekekpgspavtllirnpeeisvdiilaleskgswpistkeglpi
qgwlgtkvrtnlrrepfylvpknakdgnsfqgetwrlsfshtekyilnnhgiektccess
gakccrkeclklmkylleqlkkefqeldafcsyhvktaifhmwtqdpqdsqwdprnlssc
fdkllaffleclrtekldhyfipkfnlfsqelidrkskeflskkieyernngfpifdkl

  • Chain 'C':
    Sequence, based on SEQRES records:
    >4leyC (C:)
gsrkepdklkkvldklrlkrkdiseaaetvnkvverllrrmqkresefkgveqlntgsyy
ehvkisapnefdvmfklevprielqeyyetgafylvkfkriprgnplshflegevlsatk
mlskfrkiikeevkeikdidvsvekekpgspavtllirnpeeisvdiilaleskgswpis
tkeglpiqgwlgtkvrtnlrrepfylvpknakdgnsfqgetwrlsfshtekyilnnhgie
ktccessgakccrkeclklmkylleqlkkefqeldafcsyhvktaifhmwtqdpqdsqwd
prnlsscfdkllaffleclrtekldhyfipkfnlfsqelidrkskeflskkieyernngf
pifdkl

    Sequence, based on observed residues (ATOM records):
    >4leyC (C:)
klkkvldklrlkrkdiseaaetvnkvverllrrmqkresefkgveqlntgsyyehvkisa
pnefdvmfklevprielqeyyetgafylvkfkriprgnplshflegevlsatkmlskfrk
iikeevkeikdidvsvekekpgspavtllirnpeeisvdiilaleskgswpistkeglpi
qgwlgtkvrtnlrrepfylvpknakdgnsfqgetwrlsfshtekyilnnhgiektccess
gakccrkeclklmkylleqlkkefqeldafcsyhvktaifhmwtqdpqdsqwdprnlssc
fdkllaffleclrtekldhyfipkfnlfsqelidrkskeflskkieyernngfpifdkl

  • Chain 'D':
    Sequence, based on SEQRES records:
    >4leyD (D:)
gsrkepdklkkvldklrlkrkdiseaaetvnkvverllrrmqkresefkgveqlntgsyy
ehvkisapnefdvmfklevprielqeyyetgafylvkfkriprgnplshflegevlsatk
mlskfrkiikeevkeikdidvsvekekpgspavtllirnpeeisvdiilaleskgswpis
tkeglpiqgwlgtkvrtnlrrepfylvpknakdgnsfqgetwrlsfshtekyilnnhgie
ktccessgakccrkeclklmkylleqlkkefqeldafcsyhvktaifhmwtqdpqdsqwd
prnlsscfdkllaffleclrtekldhyfipkfnlfsqelidrkskeflskkieyernngf
pifdkl

    Sequence, based on observed residues (ATOM records):
    >4leyD (D:)
klkkvldklrlkrkdiseaaetvnkvverllrrmqkresefkgveqlntgsyyehvkisa
pnefdvmfklevprielqeyyetgafylvkfkriprgnplshflegevlsatkmlskfrk
iikeevkeikdidvsvekekpgspavtllirnpeeisvdiilaleskgswpistkeglpi
qgwlgtkvrtnlrrepfylvpknakdgnsfqgetwrlsfshtekyilnnhgiektccess
gakccrkeclklmkylleqlkkefqeldafcsyhvktaifhmwtqdpqdsqwdprnlssc
fdkllaffleclrtekldhyfipkfnlfsqelidrkskeflskkieyernngfpifdkl

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    No sequence available.

  • Chain 'I':
    No sequence available.

  • Chain 'J':
    No sequence available.

  • Chain 'K':
    No sequence available.

  • Chain 'L':
    No sequence available.