PDB entry 4lew

View 4lew on RCSB PDB site
Description: Structure of human cGAS
Deposited on 2013-06-26, released 2013-12-25
The last revision was dated 2014-01-08, with a file datestamp of 2014-01-03.
Experiment type: XRAY
Resolution: 2.04 Å
R-factor: 0.18
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cyclic GMP-AMP synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: MB21D1, C6orf150
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Cyclic GMP-AMP synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: MB21D1, C6orf150
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ZN, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4lewA (A:)
daapgasklravleklklsrddistaagmvkgvvdhlllrlkcdsafrgvgllntgsyye
hvkisapnefdvmfklevpriqleeysntrayyfvkfkrnpkenplsqflegeilsaskm
lskfrkiikeeindikdtdvimkrkrggspavtllisekisvditlalesksswpastqe
glriqnwlsakvrkqlrlkpfylvpkhakegngfqeetwrlsfshiekeilnnhgksktc
cenkeekccrkdclklmkylleqlkerfkdkkhldkfssyhvktaffhvctqnpqdsqwd
rkdlglcfdncvtyflqclrteklenyfipefnlfssnlidkrskefltkqieyernnef
pvfdef

    Sequence, based on observed residues (ATOM records):
    >4lewA (A:)
daapgasklravleklklsrddistaagmvkgvvdhlllrlkcdsafrgvgllntgyehv
kisapnefdvmfklevpriqleeysntrayyfvkfkrnpkenplsqflegeilsaskmls
kfrkiikeeindikdtdvimkrkrggspavtllisekisvditlalesksswpastqegl
riqnwlsakvrkqlrlkpfylvpkhakegngfqeetwrlsfshiekeilnnhgksktcce
nkeekccrkdclklmkylleqlkerfkdkkhldkfssyhvktaffhvctqnpqdsqwdrk
dlglcfdncvtyflqclrteklenyfipefnlfssnlidkrskefltkqieyernnefpv
fd

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4lewB (B:)
daapgasklravleklklsrddistaagmvkgvvdhlllrlkcdsafrgvgllntgsyye
hvkisapnefdvmfklevpriqleeysntrayyfvkfkrnpkenplsqflegeilsaskm
lskfrkiikeeindikdtdvimkrkrggspavtllisekisvditlalesksswpastqe
glriqnwlsakvrkqlrlkpfylvpkhakegngfqeetwrlsfshiekeilnnhgksktc
cenkeekccrkdclklmkylleqlkerfkdkkhldkfssyhvktaffhvctqnpqdsqwd
rkdlglcfdncvtyflqclrteklenyfipefnlfssnlidkrskefltkqieyernnef
pvfdef

    Sequence, based on observed residues (ATOM records):
    >4lewB (B:)
asklravleklklsrddistaagmvkgvvdhlllrlkcdsafrgvgllntgsyyehvkis
apnefdvmfklevpriqleeysntrayyfvkfkrnpkenplsqflegeilsaskmlskfr
kiikeeindikdtdvimkrkrggspavtllisekisvditlalesksswpastqeglriq
nwlsakvrkqlrlkpfylvpkhakegngfqeetwrlsfshiekeilnnhgksktccenke
ekccrkdclklmkylleqlkerfkdkkhldkfssyhvktaffhvctqnpqdsqwdrkdlg
lcfdncvtyflqclrteklenyfipefnlfssnlidkrskefltkqieyernnefpvfd