PDB entry 4lev

View 4lev on RCSB PDB site
Description: Structure of human cGAS
Deposited on 2013-06-26, released 2013-12-25
The last revision was dated 2014-01-08, with a file datestamp of 2014-01-03.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.168
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cyclic GMP-AMP synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: MB21D1, C6orf150
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8N884 (3-368)
      • expression tag (0-2)
  • Chain 'B':
    Compound: Cyclic GMP-AMP synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: MB21D1, C6orf150
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8N884 (3-368)
      • expression tag (0-2)
  • Heterogens: ZN, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records:
    >4levA (A:)
    feldaapgasklravleklklsrddistaagmvkgvvdhlllrlkcdsafrgvgllntgs
    yyehvkisapnefdvmfklevpriqleeysntrayyfvkfkrnpkenplsqflegeilsa
    skmlskfrkiikeeindikdtdvimkrkrggspavtllisekisvditlalesksswpas
    tqeglriqnwlsakvrkqlrlkpfylvpkhakegngfqeetwrlsfshiekeilnnhgks
    ktccenkeekccrkdclklmkylleqlkerfkdkkhldkfssyhvktaffhvctqnpqds
    qwdrkdlglcfdncvtyflqclrteklenyfipefnlfssnlidkrskefltkqieyern
    nefpvfdef
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records:
    >4levB (B:)
    feldaapgasklravleklklsrddistaagmvkgvvdhlllrlkcdsafrgvgllntgs
    yyehvkisapnefdvmfklevpriqleeysntrayyfvkfkrnpkenplsqflegeilsa
    skmlskfrkiikeeindikdtdvimkrkrggspavtllisekisvditlalesksswpas
    tqeglriqnwlsakvrkqlrlkpfylvpkhakegngfqeetwrlsfshiekeilnnhgks
    ktccenkeekccrkdclklmkylleqlkerfkdkkhldkfssyhvktaffhvctqnpqds
    qwdrkdlglcfdncvtyflqclrteklenyfipefnlfssnlidkrskefltkqieyern
    nefpvfdef