PDB entry 4lef

View 4lef on RCSB PDB site
Description: Crystal structure of PHOSPHOTRIESTERASE HOMOLOGY PROTEIN FROM ESCHERICHIA COLI complexed with phosphate in active site
Class: hydrolase
Keywords: PHP fold, HYDROLASE
Deposited on 2013-06-25, released 2014-06-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 1.84 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: phosphotriesterase homology protein
    Species: Escherichia coli [TaxId:83333]
    Gene: php, yhfV, b3379, JW3342
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4lefa_
  • Chain 'B':
    Compound: phosphotriesterase homology protein
    Species: Escherichia coli [TaxId:83333]
    Gene: php, yhfV, b3379, JW3342
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4lefb_
  • Chain 'C':
    Compound: phosphotriesterase homology protein
    Species: Escherichia coli [TaxId:83333]
    Gene: php, yhfV, b3379, JW3342
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4lefc_
  • Chain 'D':
    Compound: phosphotriesterase homology protein
    Species: Escherichia coli [TaxId:83333]
    Gene: php, yhfV, b3379, JW3342
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4lefd_
  • Chain 'E':
    Compound: phosphotriesterase homology protein
    Species: Escherichia coli [TaxId:83333]
    Gene: php, yhfV, b3379, JW3342
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4lefe_
  • Chain 'F':
    Compound: phosphotriesterase homology protein
    Species: Escherichia coli [TaxId:83333]
    Gene: php, yhfV, b3379, JW3342
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4leff_
  • Chain 'G':
    Compound: phosphotriesterase homology protein
    Species: Escherichia coli [TaxId:83333]
    Gene: php, yhfV, b3379, JW3342
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4lefg_
  • Chain 'H':
    Compound: phosphotriesterase homology protein
    Species: Escherichia coli [TaxId:83333]
    Gene: php, yhfV, b3379, JW3342
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4lefh_
  • Heterogens: ZN, PO4, BGC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4lefA (A:)
    msfdptgytlahehlhidlsgfknnvdcrldqyaficqemndlmtrgvrnviemtnrymg
    rnaqfmldvmretginvvactgyyqdaffpehvatrsvqelaqemvdeieqgidgtelka
    giiaeigtsegkitpleekvfiaaalahnqtgrpisthtsfstmgleqlallqahgvdls
    rvtvghcdlkdnldnilkmidlgayvqfdtigknsyypdekriamlhalrdrgllnrvml
    smditrrshlkanggygydyllttfipqlrqsgfsqadvdvmlrenpsqffq
    

    Sequence, based on observed residues (ATOM records): (download)
    >4lefA (A:)
    sfdptgytlahehlhidlsgfknnvdcrldqyaficqemndlmtrgvrnviemtnrymgr
    naqfmldvmretginvvactgyyqdaffpehvatrsvqelaqemvdeieqgidgtelkag
    iiaeigtsegkitpleekvfiaaalahnqtgrpisthtsfstmgleqlallqahgvdlsr
    vtvghcdlkdnldnilkmidlgayvqfdtigknsyypdekriamlhalrdrgllnrvmls
    mditrrshlkanggygydyllttfipqlrqsgfsqadvdvmlrenpsqffq
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4lefB (B:)
    msfdptgytlahehlhidlsgfknnvdcrldqyaficqemndlmtrgvrnviemtnrymg
    rnaqfmldvmretginvvactgyyqdaffpehvatrsvqelaqemvdeieqgidgtelka
    giiaeigtsegkitpleekvfiaaalahnqtgrpisthtsfstmgleqlallqahgvdls
    rvtvghcdlkdnldnilkmidlgayvqfdtigknsyypdekriamlhalrdrgllnrvml
    smditrrshlkanggygydyllttfipqlrqsgfsqadvdvmlrenpsqffq
    

    Sequence, based on observed residues (ATOM records): (download)
    >4lefB (B:)
    fdptgytlahehlhidlsgfknnvdcrldqyaficqemndlmtrgvrnviemtnrymgrn
    aqfmldvmretginvvactgyyqdaffpehvatrsvqelaqemvdeieqgidgtelkagi
    iaeigtsegkitpleekvfiaaalahnqtgrpisthtsfstmgleqlallqahgvdlsrv
    tvghcdlkdnldnilkmidlgayvqfdtigknsyypdekriamlhalrdrgllnrvmlsm
    ditrrshlkanggygydyllttfipqlrqsgfsqadvdvmlrenpsqffq
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >4lefC (C:)
    msfdptgytlahehlhidlsgfknnvdcrldqyaficqemndlmtrgvrnviemtnrymg
    rnaqfmldvmretginvvactgyyqdaffpehvatrsvqelaqemvdeieqgidgtelka
    giiaeigtsegkitpleekvfiaaalahnqtgrpisthtsfstmgleqlallqahgvdls
    rvtvghcdlkdnldnilkmidlgayvqfdtigknsyypdekriamlhalrdrgllnrvml
    smditrrshlkanggygydyllttfipqlrqsgfsqadvdvmlrenpsqffq
    

    Sequence, based on observed residues (ATOM records): (download)
    >4lefC (C:)
    fdptgytlahehlhidlsgfknnvdcrldqyaficqemndlmtrgvrnviemtnrymgrn
    aqfmldvmretginvvactgyyqdaffpehvatrsvqelaqemvdeieqgidgtelkagi
    iaeigtsegkitpleekvfiaaalahnqtgrpisthtsfstmgleqlallqahgvdlsrv
    tvghcdlkdnldnilkmidlgayvqfdtigknsyypdekriamlhalrdrgllnrvmlsm
    ditrrshlkanggygydyllttfipqlrqsgfsqadvdvmlrenpsqffq
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >4lefD (D:)
    msfdptgytlahehlhidlsgfknnvdcrldqyaficqemndlmtrgvrnviemtnrymg
    rnaqfmldvmretginvvactgyyqdaffpehvatrsvqelaqemvdeieqgidgtelka
    giiaeigtsegkitpleekvfiaaalahnqtgrpisthtsfstmgleqlallqahgvdls
    rvtvghcdlkdnldnilkmidlgayvqfdtigknsyypdekriamlhalrdrgllnrvml
    smditrrshlkanggygydyllttfipqlrqsgfsqadvdvmlrenpsqffq
    

    Sequence, based on observed residues (ATOM records): (download)
    >4lefD (D:)
    fdptgytlahehlhidlsgfknnvdcrldqyaficqemndlmtrgvrnviemtnrymgrn
    aqfmldvmretginvvactgyyqdaffpehvatrsvqelaqemvdeieqgidgtelkagi
    iaeigtsegkitpleekvfiaaalahnqtgrpisthtsfstmgleqlallqahgvdlsrv
    tvghcdlkdnldnilkmidlgayvqfdtigknsyypdekriamlhalrdrgllnrvmlsm
    ditrrshlkanggygydyllttfipqlrqsgfsqadvdvmlrenpsqffq
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >4lefE (E:)
    msfdptgytlahehlhidlsgfknnvdcrldqyaficqemndlmtrgvrnviemtnrymg
    rnaqfmldvmretginvvactgyyqdaffpehvatrsvqelaqemvdeieqgidgtelka
    giiaeigtsegkitpleekvfiaaalahnqtgrpisthtsfstmgleqlallqahgvdls
    rvtvghcdlkdnldnilkmidlgayvqfdtigknsyypdekriamlhalrdrgllnrvml
    smditrrshlkanggygydyllttfipqlrqsgfsqadvdvmlrenpsqffq
    

    Sequence, based on observed residues (ATOM records): (download)
    >4lefE (E:)
    fdptgytlahehlhidlsgfknnvdcrldqyaficqemndlmtrgvrnviemtnrymgrn
    aqfmldvmretginvvactgyyqdaffpehvatrsvqelaqemvdeieqgidgtelkagi
    iaeigtsegkitpleekvfiaaalahnqtgrpisthtsfstmgleqlallqahgvdlsrv
    tvghcdlkdnldnilkmidlgayvqfdtigknsyypdekriamlhalrdrgllnrvmlsm
    ditrrshlkanggygydyllttfipqlrqsgfsqadvdvmlrenpsqffq
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >4lefF (F:)
    msfdptgytlahehlhidlsgfknnvdcrldqyaficqemndlmtrgvrnviemtnrymg
    rnaqfmldvmretginvvactgyyqdaffpehvatrsvqelaqemvdeieqgidgtelka
    giiaeigtsegkitpleekvfiaaalahnqtgrpisthtsfstmgleqlallqahgvdls
    rvtvghcdlkdnldnilkmidlgayvqfdtigknsyypdekriamlhalrdrgllnrvml
    smditrrshlkanggygydyllttfipqlrqsgfsqadvdvmlrenpsqffq
    

    Sequence, based on observed residues (ATOM records): (download)
    >4lefF (F:)
    sfdptgytlahehlhidlsgfknnvdcrldqyaficqemndlmtrgvrnviemtnrymgr
    naqfmldvmretginvvactgyyqdaffpehvatrsvqelaqemvdeieqgidgtelkag
    iiaeigtsegkitpleekvfiaaalahnqtgrpisthtsfstmgleqlallqahgvdlsr
    vtvghcdlkdnldnilkmidlgayvqfdtigknsyypdekriamlhalrdrgllnrvmls
    mditrrshlkanggygydyllttfipqlrqsgfsqadvdvmlrenpsqffq
    

  • Chain 'G':
    Sequence, based on SEQRES records: (download)
    >4lefG (G:)
    msfdptgytlahehlhidlsgfknnvdcrldqyaficqemndlmtrgvrnviemtnrymg
    rnaqfmldvmretginvvactgyyqdaffpehvatrsvqelaqemvdeieqgidgtelka
    giiaeigtsegkitpleekvfiaaalahnqtgrpisthtsfstmgleqlallqahgvdls
    rvtvghcdlkdnldnilkmidlgayvqfdtigknsyypdekriamlhalrdrgllnrvml
    smditrrshlkanggygydyllttfipqlrqsgfsqadvdvmlrenpsqffq
    

    Sequence, based on observed residues (ATOM records): (download)
    >4lefG (G:)
    sfdptgytlahehlhidlsgfknnvdcrldqyaficqemndlmtrgvrnviemtnrymgr
    naqfmldvmretginvvactgyyqdaffpehvatrsvqelaqemvdeieqgidgtelkag
    iiaeigtsegkitpleekvfiaaalahnqtgrpisthtsfstmgleqlallqahgvdlsr
    vtvghcdlkdnldnilkmidlgayvqfdtigknsyypdekriamlhalrdrgllnrvmls
    mditrrshlkanggygydyllttfipqlrqsgfsqadvdvmlrenpsqffq
    

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >4lefH (H:)
    msfdptgytlahehlhidlsgfknnvdcrldqyaficqemndlmtrgvrnviemtnrymg
    rnaqfmldvmretginvvactgyyqdaffpehvatrsvqelaqemvdeieqgidgtelka
    giiaeigtsegkitpleekvfiaaalahnqtgrpisthtsfstmgleqlallqahgvdls
    rvtvghcdlkdnldnilkmidlgayvqfdtigknsyypdekriamlhalrdrgllnrvml
    smditrrshlkanggygydyllttfipqlrqsgfsqadvdvmlrenpsqffq
    

    Sequence, based on observed residues (ATOM records): (download)
    >4lefH (H:)
    fdptgytlahehlhidlsgfknnvdcrldqyaficqemndlmtrgvrnviemtnrymgrn
    aqfmldvmretginvvactgyyqdaffpehvatrsvqelaqemvdeieqgidgtelkagi
    iaeigtsegkitpleekvfiaaalahnqtgrpisthtsfstmgleqlallqahgvdlsrv
    tvghcdlkdnldnilkmidlgayvqfdtigknsyypdekriamlhalrdrgllnrvmlsm
    ditrrshlkanggygydyllttfipqlrqsgfsqadvdvmlrenpsqffq