PDB entry 4lee

View 4lee on RCSB PDB site
Description: Structure of the Als3 adhesin from Candida albicans, residues 1-313 (mature sequence), triple mutant in the binding cavity: K59M, A116V, Y301F
Deposited on 2013-06-25, released 2014-05-14
The last revision was dated 2014-07-16, with a file datestamp of 2014-07-11.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.229
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Agglutinin-like protein 3
    Species: Candida albicans [TaxId:5476]
    Gene: ALD8, ALS3
    Database cross-references and differences (RAF-indexed):
    • Uniprot O74623 (1-End)
      • expression tag (0)
      • engineered mutation (59)
      • engineered mutation (116)
      • engineered mutation (298)
  • Chain 'B':
    Compound: Agglutinin-like protein 3
    Species: Candida albicans [TaxId:5476]
    Gene: ALD8, ALS3
    Database cross-references and differences (RAF-indexed):
    • Uniprot O74623 (1-End)
      • expression tag (0)
      • engineered mutation (59)
      • engineered mutation (116)
      • engineered mutation (298)
  • Chain 'C':
    Compound: Agglutinin-like protein 3
    Species: Candida albicans [TaxId:5476]
    Gene: ALD8, ALS3
    Database cross-references and differences (RAF-indexed):
    • Uniprot O74623 (1-End)
      • expression tag (0)
      • engineered mutation (59)
      • engineered mutation (116)
      • engineered mutation (298)
  • Chain 'D':
    Compound: Agglutinin-like protein 3
    Species: Candida albicans [TaxId:5476]
    Gene: ALD8, ALS3
    Database cross-references and differences (RAF-indexed):
    • Uniprot O74623 (1-End)
      • expression tag (0)
      • engineered mutation (59)
      • engineered mutation (116)
      • engineered mutation (298)

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4leeA (A:)
gktitgvfnsfnsltwsnaatynykgpgtptwnavlgwsldgtsaspgdtftlnmpcvfm
fttsqtsvdltahgvkyatcqfqageefmtfstltctvsntltpsikalgtvtlplvfnv
ggtgssvdledskcftagtntvtfndggkkisinvdfersnvdpkgyltdsrvipslnkv
stlfvapqcangytsgtmgfantygdvqidcsnihvgitkglndwnypvssesfsytktc
ssngifityknvpagyrpfvdayisatdvnsytlsyaneytcaggywqrapftlrwtgfr
nsdagsngivivat

    Sequence, based on observed residues (ATOM records):
    >4leeA (A:)
gktitgvfnsfnsltwsnaatynykgpgtptwnavlgwsldgtsaspgdtftlnmpcvfm
fttsqtsvdltahgvkyatcqfqageefmtfstltctvsntltpsikalgtvtlplvfnv
ggtgssvdledskcftagtntvtfndggkkisinvdfersnvdpkgyltdsrvipslnkv
stlfvapqcangytsgtmgfantygdvqidcsnihvgitkglndwnypvssesfsytktc
ssngifityknvpagyrpfvdayisatdvnsytlsyaneytcaggywqrapftlrwtgfr
nsdagsngiviva

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4leeB (B:)
gktitgvfnsfnsltwsnaatynykgpgtptwnavlgwsldgtsaspgdtftlnmpcvfm
fttsqtsvdltahgvkyatcqfqageefmtfstltctvsntltpsikalgtvtlplvfnv
ggtgssvdledskcftagtntvtfndggkkisinvdfersnvdpkgyltdsrvipslnkv
stlfvapqcangytsgtmgfantygdvqidcsnihvgitkglndwnypvssesfsytktc
ssngifityknvpagyrpfvdayisatdvnsytlsyaneytcaggywqrapftlrwtgfr
nsdagsngivivat

    Sequence, based on observed residues (ATOM records):
    >4leeB (B:)
gktitgvfnsfnsltwsnaatynykgpgtptwnavlgwsldgtsaspgdtftlnmpcvfm
fttsqtsvdltahgvkyatcqfqageefmtfstltctvsntltpsikalgtvtlplvfnv
ggtgssvdledskcftagtntvtfndggkkisinvdfersnvdpkgyltdsrvipslnkv
stlfvapqcangytsgtmgfantygdvqidcsnihvgitkglndwnypvssesfsytktc
ssngifityknvpagyrpfvdayisatdvnsytlsyaneytcaggywqrapftlrwtgfr
nsdagsngiviva

  • Chain 'C':
    Sequence, based on SEQRES records:
    >4leeC (C:)
gktitgvfnsfnsltwsnaatynykgpgtptwnavlgwsldgtsaspgdtftlnmpcvfm
fttsqtsvdltahgvkyatcqfqageefmtfstltctvsntltpsikalgtvtlplvfnv
ggtgssvdledskcftagtntvtfndggkkisinvdfersnvdpkgyltdsrvipslnkv
stlfvapqcangytsgtmgfantygdvqidcsnihvgitkglndwnypvssesfsytktc
ssngifityknvpagyrpfvdayisatdvnsytlsyaneytcaggywqrapftlrwtgfr
nsdagsngivivat

    Sequence, based on observed residues (ATOM records):
    >4leeC (C:)
gktitgvfnsfnsltwsnaatynykgpgtptwnavlgwsldgtsaspgdtftlnmpcvfm
fttsqtsvdltahgvkyatcqfqageefmtfstltctvsntltpsikalgtvtlplvfnv
ggtgssvdledskcftagtntvtfndggkkisinvdfersnvdpkgyltdsrvipslnkv
stlfvapqcangytsgtmgfantygdvqidcsnihvgitkglndwnypvssesfsytktc
ssngifityknvpagyrpfvdayisatdvnsytlsyaneytcaggywqrapftlrwtgfr
nsdagsngiviva

  • Chain 'D':
    Sequence, based on SEQRES records:
    >4leeD (D:)
gktitgvfnsfnsltwsnaatynykgpgtptwnavlgwsldgtsaspgdtftlnmpcvfm
fttsqtsvdltahgvkyatcqfqageefmtfstltctvsntltpsikalgtvtlplvfnv
ggtgssvdledskcftagtntvtfndggkkisinvdfersnvdpkgyltdsrvipslnkv
stlfvapqcangytsgtmgfantygdvqidcsnihvgitkglndwnypvssesfsytktc
ssngifityknvpagyrpfvdayisatdvnsytlsyaneytcaggywqrapftlrwtgfr
nsdagsngivivat

    Sequence, based on observed residues (ATOM records):
    >4leeD (D:)
gktitgvfnsfnsltwsnaatynykgpgtptwnavlgwsldgtsaspgdtftlnmpcvfm
fttsqtsvdltahgvkyatcqfqageefmtfstltctvsntltpsikalgtvtlplvfnv
ggtgssvdledskcftagtntvtfndggkkisinvdfersnvdpkgyltdsrvipslnkv
stlfvapqcangytsgtmgfantygdvqidcsnihvgitkglndwnypvssesfsytktc
ssngifityknvpagyrpfvdayisatdvnsytlsyaneytcaggywqrapftlrwtgfr
nsdagsngiviva