PDB entry 4lc9

View 4lc9 on RCSB PDB site
Description: structural basis for regulation of human glucokinase by glucokinase regulatory protein
Deposited on 2013-06-21, released 2013-09-04
The last revision was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 3.4 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glucokinase regulatory protein
    Species: Rattus norvegicus [TaxId:10116]
    Gene: gckr
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Glucokinase
    Species: Homo sapiens [TaxId:9606]
    Gene: GCK
    Database cross-references and differences (RAF-indexed):
  • Heterogens: F6P, NA

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4lc9A (A:)
    mpgtkryqhvietpepgewelsgyeaavpiteksnpltrnldkadaekivkllgqcdaei
    fqeegqivptyqrlysesvlttmlqvagkvqevlkepdgglvvlsgggtsgrmaflmsvs
    fnqlmkglgqkplytyliaggdrsvvasreqtedsalhgieelkkvaagkkrvvvigisv
    glsapfvagqmdycmdntavflpvlvgfnpvsmarndpiedwrstfrqvaermqkmqekq
    eafvlnpaigpeglsgssrmkgggatkilletlllaahktvdqgvvssqrclleilrtfe
    rahqvtysqsskiatlmkqvgislekkgrvhlvgwqtlgiiaimdgvecihtfgadfqdi
    rgfligdhsdmfnqkdeltnqgpqftfsqddfltsilpsltetdtvvfiftlddnltevq
    alaervrekcqniqalvhstvgqslpaplkklfpslisitwpllffdyegtyvqkfqrel
    stkwvlntvstgahvllgkilqnhmldlriansklfwralamlqrfsgqskarciesllq
    aihfpqplsddvraapischvqvahekekviptallslllrcsiseakarlsaassvcev
    vrsalsgpgqkrstqaledppacgtlnslehhhhhh
    

    Sequence, based on observed residues (ATOM records):
    >4lc9A (A:)
    yqhvietpepgewelsgyeaavpiteksnpltrnldkadaekivkllgqcdaeifqeegq
    ivptyqrlysesvlttmlqvagkvqevlkepdgglvvlsgggtsgrmaflmsvsfnqlmk
    glgqkplytyliaggdrsvvasreqtedsalhgieelkkvaagkkrvvvigisvglsapf
    vagqmdycmdntavflpvlvgfnpvsmarndpiedwrstfrqvaermqkmqekqeafvln
    paigpeglsgssrmkgggatkilletlllaahktvvssqrclleilrtferahqvtysqs
    skiatlmkqvgislekkgrvhlvgwqtlgiiaimdgvecihtfgadfqdirgfligdtsi
    lpsltetdtvvfiftlddnltevqalaervrcqniqalvhstvgqslpaplkklfpslis
    itwpllffdyegtyvqkfqrelstkwvlntvstgahvllgkilqnhmldlriansklfwr
    alamlqrfsgqskarciesllqaihfpqplsddvraapischvqvahekekviptallsl
    llrcsiseakarlsaassvcevvrsal
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4lc9B (B:)
    mhhhhhhmvddrarmeaakkekveqilaefqlqeedlkkvmrrmqkemdrglrletheea
    svkmlptyvrstpegsevgdflsldlggtnfrvmlvkvgegeegqwsvktkhqmysiped
    amtgtaemlfdyisecisdfldkhqmkhkklplgftfsfpvrhedidkgillnwtkgfka
    sgaegnnvvgllrdaikrrgdfemdvvamvndtvatmiscyyedhqcevgmivgtgcnac
    ymeemqnvelvegdegrmcvntewgafgdsgeldeflleydrlvdessanpgqqlyekli
    ggkymgelvrlvllrlvdenllfhgeaseqlrtrgafetrfvsqvesdtgdrkqiynils
    tlglrpsttdcdivrracesvstraahmcsaglagvinrmresrsedvmritvgvdgsvy
    klhpsfkerfhasvrrltpsceitfieseegsgrgaalvsavackkacmlgq
    

    Sequence, based on observed residues (ATOM records):
    >4lc9B (B:)
    kkekveqilaefqlqeedlkkvmrrmqkemdrglrletheeasvkmlptyvrstpegsev
    gdflsldlggtnfrvmlvkvgegeegqwsvktkhqmysipedamtgtaemlfdyisecis
    dfldkhqmkhkklplgftfsnvvgllrdaikrrgdfemdvvamvndtvatmiscyyedhq
    cevgmivgtgcnacymeemqnvelvegdegrmcvntewgafgdsgeldeflleydrlvde
    ssanpgqqlyekliggkymgelvrlvllrlvdenllfhgeaseqlrtrgafetrfvsqve
    sdtgdrkqiynilstlglrpsttdcdivrracesvstraahmcsaglagvinrmresrse
    dvmritvgvdgsvyklhpsfkerfhasvrrltpsceitfieseegsgrgaalvsavackk
    ac