PDB entry 4lbe

View 4lbe on RCSB PDB site
Description: Structure of KcsA with R122A mutation
Class: TRANSPORT PROTEIN, membrane protein
Keywords: Metal Transport, pH-gated potassium channel, TRANSPORT PROTEIN, membrane protein
Deposited on 2013-06-20, released 2013-10-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 2.75 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fab light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 4LBE (0-218)
    Domains in SCOPe 2.08: d4lbea1, d4lbea2, d4lbea3
  • Chain 'B':
    Compound: Fab heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 4LBE (0-211)
    Domains in SCOPe 2.08: d4lbeb1, d4lbeb2
  • Chain 'C':
    Compound: pH-gated potassium channel KcsA
    Species: Streptomyces lividans [TaxId:1916]
    Gene: kcsA, skc1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A334 (Start-129)
      • engineered mutation (127)
    Domains in SCOPe 2.08: d4lbec_
  • Heterogens: F09, DGA, K, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4lbeA (A:)
qvqlqqpgaelvkpgasvklsckasgytftsdwihwvkqrpghglewigeiipsygrany
nekiqkkatltadkssstafmqlssltsedsavyycarergdgyfavwgagttvtvssak
ttppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdly
tlsssvtvpssswpsetvtcnvahpasstkvdkkivprd

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4lbeB (B:)
dilltqspailsvspgervsfscrasqsigtdihwyqqrtngsprllikyasesisgips
rfsgsgsgtdftlsinsvesedianyycqqsnrwpftfgsgtkleikradaaptvsifpp
sseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstlt
ltkdeyerhnsytceathktstspivksfnrn

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4lbeC (C:)
mhhhhhhppmlsgllarlvklllgrhgsalhwraagaatvllvivllagsylavlaerga
pgaqlitypralwwsvetattvgygdlypvtlwgrlvavvvmvagitsfglvtaalatwf
vgreqeragh

    Sequence, based on observed residues (ATOM records): (download) 
    >4lbeC (C:)
salhwraagaatvllvivllagsylavlaergapgaqlitypralwwsvetattvgygdl
ypvtlwgrlvavvvmvagitsfglvtaalatwfvgreqeragh