PDB entry 4lbd

View 4lbd on RCSB PDB site
Description: ligand-binding domain of the human retinoic acid receptor gamma bound to the synthetic agonist bms961
Class: nuclear receptor
Keywords: NUCLEAR RECEPTOR, RETINOIC ACID RECEPTOR, ALL-TRANS RETINOIC ACID, LIGAND-BINDING DOMAIN, COMPLEX, HOLO FORM, TRANSCRIPTION REGULATION, LIGAND-DEPENDENT, ACTIVE CONFORMATION, Structural Proteomics in Europe, SPINE, Structural Genomics
Deposited on 1998-02-04, released 1999-03-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.183
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: retinoic acid receptor gamma
    Species: Homo sapiens [TaxId:9606]
    Gene: HRARGAMMA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4lbda_
  • Heterogens: 961, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4lbdA (A:)
mgsshhhhhhssglvprgshmdsyelspqleelitkvskahqetfpslcqlgkyttnssa
dhrvqldlglwdkfselatkciikivefakrlpgftglsiadqitllkaacldilmlric
trytpeqdtmtfsdgltlnrtqmhnagfgpltdlvfafagqllplemddtetgllsaicl
icgdrmdleepekvdklqepllealrlyarrrrpsqpymfprmlmkitdlrgistkgaer
aitlkmeipgpmppliremlenpemfe

    Sequence, based on observed residues (ATOM records): (download) 
    >4lbdA (A:)
lspqleelitkvskahqetfpslcqlgkyttnssadhrvqldlglwdkfselatkciiki
vefakrlpgftglsiadqitllkaacldilmlrictrytpeqdtmtfsdgltlnrtqmhn
agfgpltdlvfafagqllplemddtetgllsaiclicgdrmdleepekvdklqeplleal
rlyarrrrpsqpymfprmlmkitdlrgistkgaeraitlkmeipgpmppliremlen