PDB entry 4las

View 4las on RCSB PDB site
Description: Crystal structure of a therapeutic single chain antibody in complex with 4-hydroxymethamphetamine
Class: immune system
Keywords: methamphetamine, anti-methamphetamine antibody, therapeutic antibody, scFv, IMMUNE SYSTEM
Deposited on 2013-06-20, released 2013-12-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-25, with a file datestamp of 2019-12-20.
Experiment type: XRAY
Resolution: 2.33 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: Single chain antibody fragment scFv6H4
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 4LAS (0-End)
    Domains in SCOPe 2.08: d4lash_
  • Heterogens: 1WF, HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >4lasH (H:)
evqlqesgpslvkpsqtlsltcsvtgdsvtsgywswirqfpgnkldymgyisyrgstyyn
pslksrisitrdtsknqvylqlksvssedtatyycsyfdsddyameywgqgtsvtvsggg
gsggggsggggsqivltqspaimsaspgekvtltcsasssvssshlywyqqkpgsspklw
iystsnlasgvparfsgsgsgtsysltissmeaedaasyfchqwssfpftfgsgtkleik
raphhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4lasH (H:)
evqlqesgpslvkpsqtlsltcsvtgdsvtsgywswirqfpgnkldymgyisyrgstyyn
pslksrisitrdtsknqvylqlksvssedtatyycsyfdsddyameywgqgtsvtvsggg
gsqivltqspaimsaspgekvtltcsasssvssshlywyqqkpgsspklwiystsnlasg
vparfsgsgsgtsysltissmeaedaasyfchqwssfpftfgsgtkleikra