PDB entry 4l9w

View 4l9w on RCSB PDB site
Description: Crystal Structure of H-Ras G12C, GMPPNP-bound
Class: signaling protein
Keywords: GTPase, activating mutant, SIGNALING PROTEIN
Deposited on 2013-06-18, released 2013-11-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: gtpase hras
    Species: Homo sapiens [TaxId:9606]
    Gene: HRAS, HRAS1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01112 (5-170)
      • engineered mutation (16)
    Domains in SCOPe 2.08: d4l9wa_
  • Heterogens: GNP, MG, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4l9wA (A:)
gamgsmteyklvvvgacgvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldi
ldtagqeeysamrdqymrtgegflcvfainntksfedihqyreqikrvkdsddvpmvlvg
nkcdlaartvesrqaqdlarsygipyietsaktrqgvedafytlvreirqh

    Sequence, based on observed residues (ATOM records): (download) 
    >4l9wA (A:)
mteyklvvvgacgvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildtag
qeeysamrdqymrtgegflcvfainntksfedihqyreqikrvkdsddvpmvlvgnkcdl
aartvesrqaqdlarsygipyietsaktrqgvedafytlvreirqh