PDB entry 4l6t

View 4l6t on RCSB PDB site
Description: GM1 bound form of the ECX AB5 holotoxin
Class: hydrolase
Keywords: cholera-like toxin, matrix metalloproteinase, bacterial mmp, metzincin, ab5, ob fold, transferase, toxin, protease, pentasacharide, gm1, ganglioside, oligosaccharide complex, toxilysin, hydrolase
Deposited on 2013-06-12, released 2013-11-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 1.86 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ecxa
    Species: Escherichia coli [TaxId:562]
    Gene: ecxA
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: ecxb
    Species: Escherichia coli [TaxId:562]
    Gene: ecxB
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8GAV3 (1-103)
      • initiating methionine (0)
      • expression tag (104)
    Domains in SCOPe 2.08: d4l6tb1, d4l6tb2
  • Chain 'C':
    Compound: ecxb
    Species: Escherichia coli [TaxId:562]
    Gene: ecxB
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8GAV3 (1-103)
      • initiating methionine (0)
      • expression tag (104)
    Domains in SCOPe 2.08: d4l6tc1, d4l6tc2
  • Chain 'D':
    Compound: ecxb
    Species: Escherichia coli [TaxId:562]
    Gene: ecxB
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8GAV3 (1-103)
      • initiating methionine (0)
      • expression tag (104)
    Domains in SCOPe 2.08: d4l6td1, d4l6td2
  • Chain 'E':
    Compound: ecxb
    Species: Escherichia coli [TaxId:562]
    Gene: ecxB
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8GAV3 (1-103)
      • initiating methionine (0)
      • expression tag (104)
    Domains in SCOPe 2.08: d4l6te1, d4l6te2
  • Chain 'F':
    Compound: ecxb
    Species: Escherichia coli [TaxId:562]
    Gene: ecxB
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8GAV3 (1-103)
      • initiating methionine (0)
      • expression tag (104)
    Domains in SCOPe 2.08: d4l6tf1, d4l6tf2
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4l6tB (B:)
mtpqnitdlcneyqntmiyslnkeiatyteslagkremviisfsngatfqvevpgsqhle
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    Sequence, based on observed residues (ATOM records): (download) 
    >4l6tB (B:)
mtpqnitdlcneyqntmiyslnkeiatyteslagkremviisfsngatfqvevpgsqhle
sqkrplermkdtlraayftgikisklcawtnkspnsiaaielsnl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4l6tC (C:)
mtpqnitdlcneyqntmiyslnkeiatyteslagkremviisfsngatfqvevpgsqhle
sqkrplermkdtlraayftgikisklcawtnkspnsiaaielsnlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4l6tC (C:)
mtpqnitdlcneyqntmiyslnkeiatyteslagkremviisfsngatfqvevpgsqhle
sqkrplermkdtlraayftgikisklcawtnkspnsiaaielsnl

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4l6tD (D:)
mtpqnitdlcneyqntmiyslnkeiatyteslagkremviisfsngatfqvevpgsqhle
sqkrplermkdtlraayftgikisklcawtnkspnsiaaielsnlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4l6tD (D:)
mtpqnitdlcneyqntmiyslnkeiatyteslagkremviisfsngatfqvevpgsqhle
sqkrplermkdtlraayftgikisklcawtnkspnsiaaielsnl

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4l6tE (E:)
mtpqnitdlcneyqntmiyslnkeiatyteslagkremviisfsngatfqvevpgsqhle
sqkrplermkdtlraayftgikisklcawtnkspnsiaaielsnlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4l6tE (E:)
mtpqnitdlcneyqntmiyslnkeiatyteslagkremviisfsngatfqvevpgsqhle
sqkrplermkdtlraayftgikisklcawtnkspnsiaaielsnl

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >4l6tF (F:)
mtpqnitdlcneyqntmiyslnkeiatyteslagkremviisfsngatfqvevpgsqhle
sqkrplermkdtlraayftgikisklcawtnkspnsiaaielsnlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4l6tF (F:)
mtpqnitdlcneyqntmiyslnkeiatyteslagkremviisfsngatfqvevpgsqhle
sqkrplermkdtlraayftgikisklcawtnkspnsiaaielsnl