PDB entry 4l6i

View 4l6i on RCSB PDB site
Description: methylthioadenosine phosphorylase from schistosoma mansoni in complex with adenine
Deposited on 2013-06-12, released 2014-06-25
The last revision was dated 2016-12-21, with a file datestamp of 2016-12-16.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: S-methyl-5'-thioadenosine phosphorylase
    Species: Schistosoma mansoni [TaxId:6183]
    Gene: SmMTAP
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: S-methyl-5'-thioadenosine phosphorylase
    Species: Schistosoma mansoni [TaxId:6183]
    Gene: SmMTAP
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: S-methyl-5'-thioadenosine phosphorylase
    Species: Schistosoma mansoni [TaxId:6183]
    Gene: SmMTAP
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: S-methyl-5'-thioadenosine phosphorylase
    Species: Schistosoma mansoni [TaxId:6183]
    Gene: SmMTAP
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: S-methyl-5'-thioadenosine phosphorylase
    Species: Schistosoma mansoni [TaxId:6183]
    Gene: SmMTAP
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: S-methyl-5'-thioadenosine phosphorylase
    Species: Schistosoma mansoni [TaxId:6183]
    Gene: SmMTAP
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ADE, SO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4l6iA (A:)
mgsshhhhhhssglvprgshmmskvkvgiiggsgfddpnlfkkvgvrqvttpfgkpsdtl
vegfvgdvacvvlprhgkghlippsevnyranvwalkdlgcthilatnacgslqedlvpg
dfvvlnqfmdktwgrentfygskpdslkgvlhmpmaepfcertrqiliqaarnksinvyd
kktmdksacihpcvhaegsavtingprfstrcesfihkamgldivnmtlvpevslareag
lsyasiaivtdfdcwkseeehvcvdmvleqfrksvvhvreilleavaligaedwtktiea
nkalvmssrqdllhqgsndk

    Sequence, based on observed residues (ATOM records):
    >4l6iA (A:)
kvkvgiiggsgfddpnlfkkvgvrqvttpfgkpsdtlvegfvgdvacvvlprhgkghlip
psevnyranvwalkdlgcthilatnacgslqedlvpgdfvvlnqfmdktwgrentfygsk
pdslkgvlhmpmaepfcertrqiliqaarnksinvydkktmdksacihpcvhaegsavti
ngprfstrcesfihkamgldivnmtlvpevslareaglsyasiaivtdfdcwkseeehvc
vdmvleqfrksvvhvreilleavaligaedwtktieankalvmssrqdl

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4l6iB (B:)
mgsshhhhhhssglvprgshmmskvkvgiiggsgfddpnlfkkvgvrqvttpfgkpsdtl
vegfvgdvacvvlprhgkghlippsevnyranvwalkdlgcthilatnacgslqedlvpg
dfvvlnqfmdktwgrentfygskpdslkgvlhmpmaepfcertrqiliqaarnksinvyd
kktmdksacihpcvhaegsavtingprfstrcesfihkamgldivnmtlvpevslareag
lsyasiaivtdfdcwkseeehvcvdmvleqfrksvvhvreilleavaligaedwtktiea
nkalvmssrqdllhqgsndk

    Sequence, based on observed residues (ATOM records):
    >4l6iB (B:)
mskvkvgiiggsgfddpnlfkkvgvrqvttpfgkpsdtlvegfvgdvacvvlprhgkghl
ippsevnyranvwalkdlgcthilatnacgslqedlvpgdfvvlnqfmdktwgrentfyg
skpdslkgvlhmpmaepfcertrqiliqaarnksinvydkktmdksacihpcvhaegsav
tingprfstrcesfihkamgldivnmtlvpevslareaglsyasiaivtdfdcwkseeeh
vcvdmvleqfrksvvhvreilleavaligaedwtktieankalvmssrqd

  • Chain 'C':
    Sequence, based on SEQRES records:
    >4l6iC (C:)
mgsshhhhhhssglvprgshmmskvkvgiiggsgfddpnlfkkvgvrqvttpfgkpsdtl
vegfvgdvacvvlprhgkghlippsevnyranvwalkdlgcthilatnacgslqedlvpg
dfvvlnqfmdktwgrentfygskpdslkgvlhmpmaepfcertrqiliqaarnksinvyd
kktmdksacihpcvhaegsavtingprfstrcesfihkamgldivnmtlvpevslareag
lsyasiaivtdfdcwkseeehvcvdmvleqfrksvvhvreilleavaligaedwtktiea
nkalvmssrqdllhqgsndk

    Sequence, based on observed residues (ATOM records):
    >4l6iC (C:)
kvkvgiiggsgfddpnlfkkvgvrqvttpfgkpsdtlvegfvgdvacvvlprhgkghlip
psevnyranvwalkdlgcthilatnacgslqedlvpgdfvvlnqfmdktwgrentfygsk
pdslkgvlhmpmaepfcertrqiliqaarnksinvydkktmdksacihpcvhaegsavti
ngprfstrcesfihkamgldivnmtlvpevslareaglsyasiaivtvdmvleqfrksvv
hvreilleavaligaedwtktieankalvmssrqdll

  • Chain 'D':
    Sequence, based on SEQRES records:
    >4l6iD (D:)
mgsshhhhhhssglvprgshmmskvkvgiiggsgfddpnlfkkvgvrqvttpfgkpsdtl
vegfvgdvacvvlprhgkghlippsevnyranvwalkdlgcthilatnacgslqedlvpg
dfvvlnqfmdktwgrentfygskpdslkgvlhmpmaepfcertrqiliqaarnksinvyd
kktmdksacihpcvhaegsavtingprfstrcesfihkamgldivnmtlvpevslareag
lsyasiaivtdfdcwkseeehvcvdmvleqfrksvvhvreilleavaligaedwtktiea
nkalvmssrqdllhqgsndk

    Sequence, based on observed residues (ATOM records):
    >4l6iD (D:)
vkvgiiggsgpnlfkkvgvrqvttpfgkpsdtlvegfvgdvacvvlprhgkghlippsev
nyranvwalkdlgcthilatnacgslqedlvpgdfvvlnqfmdktwgrentfygskpdsl
kgvlhmpmaepfcertrqiliqaarnksinvydkktmdksacihpcvhaegsavtingpr
fstrcesfihkamgldivnmtlvpevslareaglsyasiaivtdfdcwkseeehvcvdmv
leqfrksvvhvreilleavaligaedwtktieankalvmssrqdll

  • Chain 'E':
    Sequence, based on SEQRES records:
    >4l6iE (E:)
mgsshhhhhhssglvprgshmmskvkvgiiggsgfddpnlfkkvgvrqvttpfgkpsdtl
vegfvgdvacvvlprhgkghlippsevnyranvwalkdlgcthilatnacgslqedlvpg
dfvvlnqfmdktwgrentfygskpdslkgvlhmpmaepfcertrqiliqaarnksinvyd
kktmdksacihpcvhaegsavtingprfstrcesfihkamgldivnmtlvpevslareag
lsyasiaivtdfdcwkseeehvcvdmvleqfrksvvhvreilleavaligaedwtktiea
nkalvmssrqdllhqgsndk

    Sequence, based on observed residues (ATOM records):
    >4l6iE (E:)
kvkvgiiggsgfddpnlfkkvgvrqvttpfgkpsdtlvegfvgdvacvvlprhgkghlip
psevnyranvwalkdlgcthilatnacgslqedlvpgdfvvlnqfmdktwgrentfygsk
pdslkgvlhmpmaepfcertrqiliqaarnksinvydkktmdksacihpcvhaegsavti
ngprfstrcesfihkamgldivnmtlvpevslareaglsyasiaivtdfdcwkseeehvc
vdmvleqfrksvvhvreilleavaligaedwtktieankalvmssrqd

  • Chain 'F':
    Sequence, based on SEQRES records:
    >4l6iF (F:)
mgsshhhhhhssglvprgshmmskvkvgiiggsgfddpnlfkkvgvrqvttpfgkpsdtl
vegfvgdvacvvlprhgkghlippsevnyranvwalkdlgcthilatnacgslqedlvpg
dfvvlnqfmdktwgrentfygskpdslkgvlhmpmaepfcertrqiliqaarnksinvyd
kktmdksacihpcvhaegsavtingprfstrcesfihkamgldivnmtlvpevslareag
lsyasiaivtdfdcwkseeehvcvdmvleqfrksvvhvreilleavaligaedwtktiea
nkalvmssrqdllhqgsndk

    Sequence, based on observed residues (ATOM records):
    >4l6iF (F:)
kvkvgiiggsgfddpnlfkkvgvrqvttpfgkpsdtlvegfvgdvacvvlprhgkghlip
psevnyranvwalkdlgcthilatnacgslqedlvpgdfvvlnqfmdktwgrentfygsk
pdslkgvlhmpmaepfcertrqiliqaarnksinvydkktmdksacihpcvhaegsavti
ngprfstrcesfihkamgldivnmtlvpevslareaglsyasiaivtdfdcvdmvleqfr
ksvvhvreilleavaligaedwtktieankalvmssrqdllhqgsndk