PDB entry 4l6c

View 4l6c on RCSB PDB site
Description: Crystal structure of human mitochondrial deoxyribonucleotidase in complex with the inhibitor pib-t
Class: hydrolase/hydrolase inhibitor
Keywords: 5'-NUCLEOTIDASE, MITOCHONDRIA, PROTEIN CONFORMATION, SEQUENCE HOMOLOGY, HAD-LIKE, HYDROLASE, DEPHOSPHORYLATION, PHOSPHORYLATION, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2013-06-12, released 2014-09-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-10-08, with a file datestamp of 2014-10-03.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.151
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 5'(3')-deoxyribonucleotidase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: DNT2, NT5M
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NPB1 (5-End)
      • expression tag (0-4)
    Domains in SCOPe 2.08: d4l6ca1, d4l6ca2
  • Heterogens: MG, PO4, 0BT, GOL, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4l6cA (A:)
snaasggralrvlvdmdgvladfeggflrkfrarfpdqpfialedrrgfwvseqygrlrp
glsekaisiwesknfffeleplpgaveavkemaslqntdvfictspikmfkycpyekyaw
vekyfgpdfleqivltrdktvvsadlliddrpditgaeptpswehvlftachnqhlqlqp
prrrlhswaddwkaildskrpc

    Sequence, based on observed residues (ATOM records): (download) 
    >4l6cA (A:)
snaasggralrvlvdmdgvladfeggflrkfrarfpdqpfialedrrgfwvseqygrlrp
glsekaisiwesknfffeleplpgaveavkemaslqntdvfictspikmfkycpyekyaw
vekyfgpdfleqivltrdktvvsadlliddrpditgaeptpswehvlftachnqhlqlqp
prrrlhswaddwkaildskrp