PDB entry 4l64

View 4l64 on RCSB PDB site
Description: Crystal structure of the Candida albicans Methionine Synthase in complex with 5-Methyl-Tetrahydrofolate
Class: Transferase
Keywords: cobalamin-independent, surface entropy reduction, fungal, Dual TIM Barrels, Methionine synthase, Transferase
Deposited on 2013-06-11, released 2014-03-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-04-09, with a file datestamp of 2014-04-04.
Experiment type: XRAY
Resolution: 2.18 Å
R-factor: 0.184
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
    Species: Candida albicans SC5314 [TaxId:237561]
    Gene: CaO19.10083, CaO19.2551, MET6
    Database cross-references and differences (RAF-indexed):
    • Uniprot P82610 (22-End)
      • engineered mutation (124-125)
    Domains in SCOPe 2.08: d4l64a1, d4l64a2
  • Heterogens: ZN, C2F, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4l64A (A:)
mhhhhhhssgvdlgtenlyfqsmvqssvlgfpriggqrelkkiteaywsgkatveellak
gkelrehnwklqqkagvdiipsndfsyydqvldlsllfnaiperytkfdlapidvlfamg
rglqaaatatqaavdvtalemvkwfdsnyhyvrptfshstefklntaagikpvdefneak
algvqtrpvilgpvsylylgkadkdsldlepisllpkilpvykellqklkeagaeqvqid
epvlvldlpeavqskfkeaydalvgadvpelilttyfgdvrpnlkaienlpvagfhfdfv
rvpeqldevasilkdgqtlsagvvdgrniwktdfakasavvqkaiekvgkdkvvvatsss
llhtpvdlesetkldavikdwfsfatqkldevvviaknvsgedvskqleanaasikarse
ssitndpkvqerlttinealatrkaafperlteqkakynlplfptttigsfpqtkdirin
rnkfakgqitaeeyeafinkeietvvrfqeeigldvlvhgeperndmvqyfgeqlngfaf
ttngwvqsygsryvrppiivgdvsrpkamtvkesvyaqsitskpmkgmltgpvtilrwsf
prddvsgkiqalqlglalrdevndlegagitviqvdepaireglplragkersdylnwaa
qsfrvatsgvenstqihshfcysdldpnhikaldadvvsiefskkddpnyiqefseypnh
iglglfdihspripskqefvsrieeilkvypaskfwvnpdcglktrgwpevkesltnmve
aakefraky

    Sequence, based on observed residues (ATOM records): (download) 
    >4l64A (A:)
mvqssvlgfpriggqrelkkiteaywsgkatveellakgkelrehnwklqqkagvdiips
ndfsyydqvldlsllfnaiperytkfdlapidvlfamgrglqaaqaavdvtalemvkwfd
snyhyvrptfshstefklntaagikpvdefneakalgvqtrpvilgpvsylylgkadkds
ldlepisllpkilpvykellqklkeagaeqvqidepvlvldlpeavqskfkeaydalvga
dvpelilttyfgdvrpnlkaienlpvagfhfdfvrvpeqldevasilkdgqtlsagvvdg
rniwktdfakasavvqkaiekvgkdkvvvatsssllhtpvdlesetkldavikdwfsfat
qkldevvviaknvsgedvskqleanaasikarsessitndpkvqerlttinealatrkaa
fperlteqkakynlplfptttigsfpkdirinrnkfakgqitaeeyeafinkeietvvrf
qeeigldvlvhgeperndmvqyfgeqlngfafttngwvqsygsryvrppiivgdvsrpka
mtvkesvyaqsitskpmkgmltgpvtilrwsfprddvsgkiqalqlglalrdevndlega
gitviqvdepaireglplragkersdylnwaaqsfrvatsgvenstqihshfcydpnhik
aldadvvsieefseypnhiglglfpskqefvsrieeilkpaskfwvnpdcglrgwpevke
sltnmveaakefr