PDB entry 4l5u
View 4l5u on RCSB PDB site
Description: The structural implications of the secondary CO2 binding pocket in human carbonic anhydrase II
Class: Lyase
Keywords: allosteric regulation, thermostability, Lyase
Deposited on
2013-06-11, released
2014-04-30
The last revision prior to the SCOPe 2.08 freeze date was dated
2014-04-30, with a file datestamp of
2014-04-25.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: 0.156
AEROSPACI score: 0.4
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Carbonic anhydrase 2
Species: Homo sapiens [TaxId:9606]
Gene: CA2
Database cross-references and differences (RAF-indexed):
- Uniprot P00918 (Start-259)
- engineered mutation (224)
Domains in SCOPe 2.08: d4l5ua_ - Heterogens: ZN, GOL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4l5uA (A:)
mshhwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslril
nnghafnvefddsqdkavlkggpldgtyrliqfhfhwgsldgqgsehtvdkkkyaaelhl
vhwntkygdfgkavqqpdglavlgiflkvgsakpglqkvvdvldsiktkgksadftnfdp
rgllpesldywtypgslttppllecvtwivlkepisvsseqvlkirklnfngegepeelm
vdnwrpaqplknrqikasfk
Sequence, based on observed residues (ATOM records): (download)
>4l5uA (A:)
hwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslrilnng
hafnvefddsqdkavlkggpldgtyrliqfhfhwgsldgqgsehtvdkkkyaaelhlvhw
ntkygdfgkavqqpdglavlgiflkvgsakpglqkvvdvldsiktkgksadftnfdprgl
lpesldywtypgslttppllecvtwivlkepisvsseqvlkirklnfngegepeelmvdn
wrpaqplknrqikasfk