PDB entry 4l45

View 4l45 on RCSB PDB site
Description: Crystal structures of human p70S6K1-T389E
Class: transferase
Keywords: Protein kinase, TRANSFERASE
Deposited on 2013-06-07, released 2013-07-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: RPS6KB1 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: RPS6KB1, hCG_1815774
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7Z721 (Start-345)
      • engineered mutation (340)
    Domains in SCOPe 2.08: d4l45a_
  • Heterogens: 5FI

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4l45A (A:)
gamsetsvnrgpekirpecfellrvlgkggygkvfqvrkvtgantgkifamkvlkkamiv
rnakdtahtkaernileevkhpfivdliyafqtggklylileylsggelfmqleregifm
edtacfylaeismalghlhqkgiiyrdlkpenimlnhqghvkltdfglckesihdgtvth
tfcgtieymapeilmrsghnravdwwslgalmydmltgappftgenrkktidkilkckln
lppyltqeardllkkllkrnaasrlgagpgdagevqahpffrhinweellarkveppfkp
llqseedvsqfdskftrqtpvdspddstlsesanqvflgfeyvaps

    Sequence, based on observed residues (ATOM records): (download) 
    >4l45A (A:)
rgpekirpecfellrvlgkggygkvfqvrkvtgantgkifamkvlkkamivrnakdtaht
kaernileevkhpfivdliyafqtggklylileylsggelfmqleregifmedtacfyla
eismalghlhqkgiiyrdlkpenimlnhqghvkltdfglckesgtieymapeilmrsghn
ravdwwslgalmydmltgappftgenrkktidkilkcklnlppyltqeardllkkllkrn
aasrlgagpgdagevqahpffrhinweellarkveppfkpllqseedvsqfdskftrqtp
vesanqvflgfeyvaps