PDB entry 4l43

View 4l43 on RCSB PDB site
Description: Crystal structures of human p70S6K1-T389A (form I)
Class: transferase
Keywords: Protein kinase, TRANSFERASE
Deposited on 2013-06-07, released 2013-07-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 3 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: RPS6KB1 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: RPS6KB1, hCG_1815774
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7Z721 (Start-345)
      • engineered mutation (340)
    Domains in SCOPe 2.08: d4l43a_
  • Heterogens: 5FI

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4l43A (A:)
    gamsetsvnrgpekirpecfellrvlgkggygkvfqvrkvtgantgkifamkvlkkamiv
    rnakdtahtkaernileevkhpfivdliyafqtggklylileylsggelfmqleregifm
    edtacfylaeismalghlhqkgiiyrdlkpenimlnhqghvkltdfglckesihdgtvth
    tfcgtieymapeilmrsghnravdwwslgalmydmltgappftgenrkktidkilkckln
    lppyltqeardllkkllkrnaasrlgagpgdagevqahpffrhinweellarkveppfkp
    llqseedvsqfdskftrqtpvdspddstlsesanqvflgfayvaps
    

    Sequence, based on observed residues (ATOM records): (download)
    >4l43A (A:)
    rgpekirpecfellrvlgkggygkvfqvrkvtgantgkifamkvlkkamivrnakdtaht
    kaernileevkhpfivdliyafqtggklylileylsggelfmqleregifmedtacfyla
    eismalghlhqkgiiyrdlkpenimlnhqghvkltdfglckesgtieymapeilmrsghn
    ravdwwslgalmydmltgappftgenrkktidkilkcklnlppyltqeardllkkllkrn
    aasrlgagpgdagevqahpffrhinweellarkveppfkpllqseedvsqfdskftrqtp
    vsanqvflgfayvaps