PDB entry 4l3t

View 4l3t on RCSB PDB site
Description: Crystal Structure of Substrate-free Human Presequence Protease
Deposited on 2013-06-06, released 2013-07-03
The last revision was dated 2014-07-23, with a file datestamp of 2014-07-18.
Experiment type: XRAY
Resolution: 2.03 Å
R-factor: 0.173
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Presequence protease, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: KIAA1104, MP1, PITRM1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5JRX3 (9-1013)
      • expression tag (8)
      • engineered mutation (83)
      • see remark 999 (304)
      • see remark 999 (373)
      • see remark 999 (1013)
  • Chain 'B':
    Compound: Presequence protease, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: KIAA1104, MP1, PITRM1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5JRX3 (9-1013)
      • expression tag (7-8)
      • engineered mutation (83)
      • see remark 999 (304)
      • see remark 999 (373)
      • see remark 999 (1013)
  • Heterogens: ZN, GOL, ACT, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4l3tA (A:)
mhhhhhhaaaceralqyklgdkihgftvnqvtsvpelfltavklthddtgarylhlared
tnnlfsvqfrttpmdstgvphilqhtvlcgsqkypcrdpffkmlnrslstfmnaftasdy
tlypfstqnpkdfqnllsvyldatffpclreldfwqegwrlehenpsdpqtplvfkgvvf
nemkgaftdnerifsqhlqnrllpdhtysvvsggdplcipeltweqlkqfhathyhpsna
rfftygnfpleqhlkqiheealskfqkiepstvvpaqtpwdkprefqitcgpdsfatdps
kqttvsvsfllpditdtfeaftlsllsslltsgpnspfykaliesglgtdfspdvgyngy
treayfsvglqgivekdietvrslidrtidevvekgfeddrieallhkieiqmkhqstsf
glmltsyiascwnhdgdpvellklgnqlakfrqclqenpkflqekvkqyfknnqhkltls
mrpddkyhekqaqveatklkqkvealspgdrqqiyekglelrsqqskpqdasclpalkvs
dieptipvteldvvltagdipvqycaqptngmvyfrafsslntlpeelrpyvplfcsvlt
klgcglldyreqaqqielktggmsasphvlpddshmdtyeqgvlfsslcldrnlpdmmql
wseifnnpcfeeeehfkvlvkmtaqelangipdsghlyasiragrtltpagdlqetfsgm
dqvrlmkriaemtdikpilrklprikkhllngdnmrcsvnatpqqmpqtekavedflrsi
grskkerrpvrphtvekpvpsssggdahvphgsqvirklvmeptfkpwqmkthflmpfpv
nyvgecirtvpytdpdhaslkilarlmtakflhteirekggaygggaklshngiftlysy
rdpntietlqsfgkavdwaksgkftqqdideaklsvfstvdapvapsdkgmdhflyglsd
emkqahreqlfavshdkllavsdrylgtgksthglailgpenpkiakdpswiir

    Sequence, based on observed residues (ATOM records):
    >4l3tA (A:)
aaceralqyklgdkihgftvnqvtsvpelfltavklthddtgarylhlaredtnnlfsvq
frttpmdstgvphilqhtvlcgsqkypcrdpffkmlnrslstfmnaftasdytlypfstq
npkdfqnllsvyldatffpclreldfwqegwrlehenpsdpqtplvfkgvvfnemkgaft
dnerifsqhlqnrllpdhtysvvsggdplcipeltweqlkqfhathyhpsnarfftygnf
pleqhlkqiheealskfqkiepstvvpaqtpwdkprefqitcgpdkqttvsvsfllpdit
dtfeaftlsllsslltsgpnspfykaliesglgtdfspdvgyngytreayfsvglqgive
kdietvrslidrtidevvekgfeddrieallhkieiqmkhqstsfglmltsyiascwnhd
gdpvellklgnqlakfrqclqenpkflqekvkqyfknnqhkltlsmrpddkyhekqaqve
atklkqkvealspgdrqqiyekglelrsqqskpqdasclpalkvsdieptipvteldvvl
tagdipvqycaqptngmvyfrafsslntlpeelrpyvplfcsvltklgcglldyreqaqq
ielktggmsasphvlpddshmdtyeqgvlfsslcldrnlpdmmqlwseifnnpcfeeeeh
fkvlvkmtaqelangipdsghlyasiragrtltpagdlqetfsgmdqvrlmkriaemtdi
kpilrklprikkhllngdnmrcsvnatpqqmpqtekavedflrsigrsrpvrphtvekpv
pvirklvmeptfkpwqmkthflmpfpvnyvgecirtvpytdpdhaslkilarlmtakflh
teirekggaygggaklshngiftlysyrdpntietlqsfgkavdwaksgkftqqdideak
lsvfstvdapvapsdkgmdhflyglsdemkqahreqlfavshdkllavsdrylgtgksth
glailgpenpkiakdpswiir

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4l3tB (B:)
mhhhhhhaaaceralqyklgdkihgftvnqvtsvpelfltavklthddtgarylhlared
tnnlfsvqfrttpmdstgvphilqhtvlcgsqkypcrdpffkmlnrslstfmnaftasdy
tlypfstqnpkdfqnllsvyldatffpclreldfwqegwrlehenpsdpqtplvfkgvvf
nemkgaftdnerifsqhlqnrllpdhtysvvsggdplcipeltweqlkqfhathyhpsna
rfftygnfpleqhlkqiheealskfqkiepstvvpaqtpwdkprefqitcgpdsfatdps
kqttvsvsfllpditdtfeaftlsllsslltsgpnspfykaliesglgtdfspdvgyngy
treayfsvglqgivekdietvrslidrtidevvekgfeddrieallhkieiqmkhqstsf
glmltsyiascwnhdgdpvellklgnqlakfrqclqenpkflqekvkqyfknnqhkltls
mrpddkyhekqaqveatklkqkvealspgdrqqiyekglelrsqqskpqdasclpalkvs
dieptipvteldvvltagdipvqycaqptngmvyfrafsslntlpeelrpyvplfcsvlt
klgcglldyreqaqqielktggmsasphvlpddshmdtyeqgvlfsslcldrnlpdmmql
wseifnnpcfeeeehfkvlvkmtaqelangipdsghlyasiragrtltpagdlqetfsgm
dqvrlmkriaemtdikpilrklprikkhllngdnmrcsvnatpqqmpqtekavedflrsi
grskkerrpvrphtvekpvpsssggdahvphgsqvirklvmeptfkpwqmkthflmpfpv
nyvgecirtvpytdpdhaslkilarlmtakflhteirekggaygggaklshngiftlysy
rdpntietlqsfgkavdwaksgkftqqdideaklsvfstvdapvapsdkgmdhflyglsd
emkqahreqlfavshdkllavsdrylgtgksthglailgpenpkiakdpswiir

    Sequence, based on observed residues (ATOM records):
    >4l3tB (B:)
aaaceralqyklgdkihgftvnqvtsvpelfltavklthddtgarylhlaredtnnlfsv
qfrttpmdstgvphilqhtvlcgsqkypcrdpffkmlnrslstfmnaftasdytlypfst
qnpkdfqnllsvyldatffpclreldfwqegwrlehenpsdpqtplvfkgvvfnemkgaf
tdnerifsqhlqnrllpdhtysvvsggdplcipeltweqlkqfhathyhpsnarfftygn
fpleqhlkqiheealskfqkiepstvvpaqtpwdkprefqitcgpdkqttvsvsfllpdi
tdtfeaftlsllsslltsgpnspfykaliesglgtdfspdvgyngytreayfsvglqgiv
ekdietvrslidrtidevvekgfeddrieallhkieiqmkhqstsfglmltsyiascwnh
dgdpvellklgnqlakfrqclqenpkflqekvkqyfknnqhkltlsmrpddkyhekqaqv
eatklkqkvealspgdrqqiyekglelrsqqskpqdasclpalkvsdieptipvteldvv
ltagdipvqycaqptngmvyfrafsslntlpeelrpyvplfcsvltklgcglldyreqaq
qielktggmsasphvlpddshmdtyeqgvlfsslcldrnlpdmmqlwseifnnpcfeeee
hfkvlvkmtaqelangipdsghlyasiragrtltpagdlqetfsgmdqvrlmkriaemtd
ikpilrklprikkhllngdnmrcsvnatpqqmpqtekavedflrsigrspvrhtvekpvi
rklvmeptfkpwqmkthflmpfpvnyvgecirtvpytdpdhaslkilarlmtakflhtei
rekggaygggaklshngiftlysyrdpntietlqsfgkavdwaksgkftqqdideaklsv
fstvdapvapsdkgmdhflyglsdemkqahreqlfavshdkllavsdrylgtgksthgla
ilgpenpkiakdpswiir