PDB entry 4l2w

View 4l2w on RCSB PDB site
Description: Crystal structure of the Shroom-Binding domain of human Rock1
Deposited on 2013-06-04, released 2014-04-16
The last revision was dated 2014-04-16, with a file datestamp of 2014-04-11.
Experiment type: XRAY
Resolution: 2.49 Å
R-factor: 0.238
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Rho-associated protein kinase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: ROCK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13464
      • engineered mutation (56-58)
  • Chain 'B':
    Compound: Rho-associated protein kinase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: ROCK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13464
      • engineered mutation (56-58)
  • Chain 'C':
    Compound: Rho-associated protein kinase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: ROCK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13464
      • engineered mutation (56-58)
  • Chain 'D':
    Compound: Rho-associated protein kinase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: ROCK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13464
      • engineered mutation (56-58)
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4l2wA (A:)
gidpftgnegqmrelqdqleaeqyfstlyktqvkelkeeieeknrenlkkiqelqnaaat
latqldlaetkaeseqlarglleeqyf

    Sequence, based on observed residues (ATOM records):
    >4l2wA (A:)
gqmrelqdqleaeqyfstlyktqvkelkeeieeknrenlkkiqelqnaaatlatqldlae
tkaeseq

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4l2wB (B:)
gidpftgnegqmrelqdqleaeqyfstlyktqvkelkeeieeknrenlkkiqelqnaaat
latqldlaetkaeseqlarglleeqyf

    Sequence, based on observed residues (ATOM records):
    >4l2wB (B:)
qmrelqdqleaeqyfstlyktqvkelkeeieeknrenlkkiqelqnaaatlatqldlaet
kaeseql

  • Chain 'C':
    Sequence, based on SEQRES records:
    >4l2wC (C:)
gidpftgnegqmrelqdqleaeqyfstlyktqvkelkeeieeknrenlkkiqelqnaaat
latqldlaetkaeseqlarglleeqyf

    Sequence, based on observed residues (ATOM records):
    >4l2wC (C:)
qmrelqdqleaeqyfstlyktqvkelkeeieeknrenlkkiqelqnaaatlatqldlaet
kaeseql

  • Chain 'D':
    Sequence, based on SEQRES records:
    >4l2wD (D:)
gidpftgnegqmrelqdqleaeqyfstlyktqvkelkeeieeknrenlkkiqelqnaaat
latqldlaetkaeseqlarglleeqyf

    Sequence, based on observed residues (ATOM records):
    >4l2wD (D:)
negqmrelqdqleaeqyfstlyktqvkelkeeieeknrenlkkiqelqnaaatlatqldl
aetkaese