PDB entry 4l1w
View 4l1w on RCSB PDB site
Description: Crystal Structuer of Human 3-alpha Hydroxysteroid Dehydrogenase Type 3 in Complex with NADP+ and Progesterone
Class: oxidoreductase
Keywords: alpha-beta barrel, human 3-alpha hsd3, akr, akr1c2,oxidoreductase, aldo-keto reductase, nadph, oxidoreductase
Deposited on
2013-06-03, released
2014-04-16
The last revision prior to the SCOPe 2.07 freeze date was dated
2014-04-16, with a file datestamp of
2014-04-11.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.148
AEROSPACI score: 0.37
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Aldo-keto reductase family 1 member C2
Species: Homo sapiens [TaxId:9606]
Gene: AKR1C2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d4l1wa1, d4l1wa2 - Chain 'B':
Compound: Aldo-keto reductase family 1 member C2
Species: Homo sapiens [TaxId:9606]
Gene: AKR1C2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d4l1wb1, d4l1wb2 - Heterogens: NAP, STR, SO4, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>4l1wA (A:)
svddskyqcvklndghfmpvlgfgtyapaevpkskaleavklaieagfhhidsahvynne
eqvglairskiadgsvkredifytsklwsnshrpelvrpalerslknlqldyvdlylihf
pvsvkpgeevipkdengkilfdtvdlcatweamekckdaglaksigvsnfnhrllemiln
kpglkykpvcnqvechpyfnqrklldfckskdivlvaysalgshreepwvdpnspvlled
pvlcalakkhkrtpalialryqlqrgvvvlaksyneqrirqnvqvfefqltseemkaidg
lnrnvryltldifagppnypfsdey
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>4l1wB (B:)
svddskyqcvklndghfmpvlgfgtyapaevpkskaleavklaieagfhhidsahvynne
eqvglairskiadgsvkredifytsklwsnshrpelvrpalerslknlqldyvdlylihf
pvsvkpgeevipkdengkilfdtvdlcatweamekckdaglaksigvsnfnhrllemiln
kpglkykpvcnqvechpyfnqrklldfckskdivlvaysalgshreepwvdpnspvlled
pvlcalakkhkrtpalialryqlqrgvvvlaksyneqrirqnvqvfefqltseemkaidg
lnrnvryltldifagppnypfsdey