PDB entry 4l1j

View 4l1j on RCSB PDB site
Description: Three dimensional structure of mutant D143A of human HD domain-containing protein 2, Northeast Structural Genomics Consortium (NESG) Target HR6723
Deposited on 2013-06-03, released 2013-06-19
The last revision was dated 2013-12-25, with a file datestamp of 2013-12-20.
Experiment type: XRAY
Resolution: 1.82 Å
R-factor: 0.177
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HD domain-containing protein 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7Z4H3
      • engineered mutation (142)
  • Chain 'B':
    Compound: HD domain-containing protein 2 (Phosphorylate)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7Z4H3
      • engineered mutation (142)
  • Heterogens: PEG, PE4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4l1jA (A:)
masvssatfsghgarsllqflrlvgqlkrvprtgwvyrnvqrpesvsdhmyrmavmamvi
kddrlnkdrcvrlalvhdmaecivgdiapadnipkeekhrreeeamkqitqllpedlrke
lyelweeyetqssaeakfvkqlaqcemilqaseyedlehkpgrlqdfydstagkfnhpei
vqlvseleaerstniaaaasephs

    Sequence, based on observed residues (ATOM records):
    >4l1jA (A:)
garsllqflrlvgqlkrvprtgwvyrnvqrpesvsdhmyrmavmamvikddrlnkdrcvr
lalvhdmaecivgdiapadnipkeekhrreeeamkqitqllpedlrkelyelweeyetqs
saeakfvkqlaqcemilqaseyedlehkpgrlqdfydstagkfnhpeivqlvseleaers
tniaaaas

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4l1jB (B:)
masvssatfsghgarsllqflrlvgqlkrvprtgwvyrnvqrpesvsdhmyrmavmamvi
kddrlnkdrcvrlalvhdmaecivgdiapadnipkeekhrreeeamkqitqllpedlrke
lyelweeyetqssaeakfvkqlaqcemilqaseyedlehkpgrlqdfydstagkfnhpei
vqlvseleaerstniaaaasephs

    Sequence, based on observed residues (ATOM records):
    >4l1jB (B:)
satfsghgarsllqflrlvgqlkrvprtgwvyrnvqrpesvsdhmyrmavmamvikddrl
nkdrcvrlalvhdmaecivgdiapadnipkeekhrreeeamkqitqllpedlrkelyelw
eeyetqssaeakfvkqlaqcemilqaseyedlehkpgrlqdfydstagkfnhpeivqlvs
eleaerstniaaaas