PDB entry 4l0s

View 4l0s on RCSB PDB site
Description: Tankyrase 2 in complex with 4'-cyano flavone
Deposited on 2013-06-01, released 2013-10-30
The last revision was dated 2014-01-15, with a file datestamp of 2014-01-10.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.162
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tankyrase-2
    Species: Homo sapiens [TaxId:9606]
    Gene: TNKS2, PARP5B, TANK2, TNKL
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: tankyrase-2
    Species: Homo sapiens [TaxId:9606]
    Gene: TNKS2, PARP5B, TANK2, TNKL
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: tankyrase-2
    Species: Homo sapiens [TaxId:9606]
    Gene: TNKS2, PARP5B, TANK2, TNKL
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: tankyrase-2
    Species: Homo sapiens [TaxId:9606]
    Gene: TNKS2, PARP5B, TANK2, TNKL
    Database cross-references and differences (RAF-indexed):
  • Heterogens: 1UZ, ZN, SO4, GOL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4l0sA (A:)
mhhhhhhssgvdlgtenlyfqsmlntsgsgtilidlspddkefqsveeemqstvrehrdg
ghaggifnrynilkiqkvcnkklwerythrrkevseenhnhanermlfhgspfvnaiihk
gfderhayiggmfgagiyfaenssksnqyvygigggtgcpvhkdrscyichrqllfcrvt
lgksflqfsam

    Sequence, based on observed residues (ATOM records):
    >4l0sA (A:)
gtilidlspddkefqsveeemqstvrehrdgghaggifnrynilkiqkvcnkklweryth
rrkevseenhnhanermlfhgspfvnaiihkgfderhayiggmfgagiyfaenssksnqy
vygigggtgcpvhkdrscyichrqllfcrvtlgksflqfsa

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4l0sB (B:)
mhhhhhhssgvdlgtenlyfqsmlntsgsgtilidlspddkefqsveeemqstvrehrdg
ghaggifnrynilkiqkvcnkklwerythrrkevseenhnhanermlfhgspfvnaiihk
gfderhayiggmfgagiyfaenssksnqyvygigggtgcpvhkdrscyichrqllfcrvt
lgksflqfsam

    Sequence, based on observed residues (ATOM records):
    >4l0sB (B:)
gtilidlspddkefqsveeemqstvrehrdgghaggifnrynilkiqkvcnkklweryth
rrkevseenhnhanermlfhgspfvnaiihkgfderhayiggmfgagiyfaenssksnqy
vygigggtgcpvhkdrscyichrqllfcrvtlgksflqfsam

  • Chain 'C':
    Sequence, based on SEQRES records:
    >4l0sC (C:)
kmahsppghhsvtgrpsvnglalaeyviyrgeqaypeylityqimrpeg

    Sequence, based on observed residues (ATOM records):
    >4l0sC (C:)
mahsppghhsvtgrpsvnglalaeyviyrgeqaypeylityqimrpe

  • Chain 'D':
    Sequence, based on SEQRES records:
    >4l0sD (D:)
kmahsppghhsvtgrpsvnglalaeyviyrgeqaypeylityqimrpeg

    Sequence, based on observed residues (ATOM records):
    >4l0sD (D:)
mahsppghhsvtgrpsvnglalaeyviyrgeqaypeylityqimrpe