PDB entry 4l0p

View 4l0p on RCSB PDB site
Description: Structure of the human EphA3 receptor ligand binding domain complexed with ephrin-A5
Class: transferase/transferase receptor
Keywords: beta-sandwich, Receptor Tyrosine Kinase, ephrin binding, TRANSFERASE-TRANSFERASE RECEPTOR complex
Deposited on 2013-05-31, released 2014-06-11
The last revision prior to the SCOPe 2.04 freeze date was dated 2014-06-11, with a file datestamp of 2014-06-06.
Experiment type: XRAY
Resolution: 2.26 Å
R-factor: 0.188
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ephrin type-A receptor 3
    Species: Homo sapiens [TaxId:9606]
    Gene: EPHA3, EPHA3_HUMAN, ETK, ETK1, HEK, TYRO4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P29320 (3-175)
      • expression tag (1-2)
    Domains in SCOPe 2.04: d4l0pa_
  • Chain 'B':
    Compound: Ephrin-A5
    Species: Homo sapiens [TaxId:9606]
    Gene: EFNA5, EFNA5_HUMAN, EPLG7, LERK7
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4l0pb_
  • Heterogens: SO4, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4l0pA (A:)
    gsgevnlldsktiqgelgwisypshgweeisgvdehytpirtyqvcnvmdhsqnnwlrtn
    wvprnsaqkiyvelkftlrdcnsiplvlgtcketfnlyymesdddhgvkfrehqftkidt
    iaadesftqmdlgdrilklnteirevgpvnkkgfylafqdvgacvalvsvrvyfkk
    

    Sequence, based on observed residues (ATOM records): (download)
    >4l0pA (A:)
    sgevnlldsktiqgelgwisypshgweeisgvdehytpirtyqvcnvmdhsqnnwlrtnw
    vprnsaqkiyvelkftlrdcnsiplvlgtcketfnlyymesdddhgvkfrehqftkidti
    aadesftqmdlgdrilklnteirevgpvnkkgfylafqdvgacvalvsvrvyfkk
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4l0pB (B:)
    gsgavadryavywnssnprfqrgdyhidvcindyldvfcphyedsvpedkteryvlymvn
    fdgysacdhtskgfkrwecnrphspngplkfsekfqlftpfslgfefrpgreyfyissai
    pdngrrsclklkvfvrptnscmk
    

    Sequence, based on observed residues (ATOM records): (download)
    >4l0pB (B:)
    avadryavywnssnprfqrgdyhidvcindyldvfcphyedsvpedkteryvlymvnfdg
    ysacdhtskgfkrwecnrphspngplkfsekfqlftpfslgfefrpgreyfyissaipdn
    grrsclklkvfvrptnscm