PDB entry 4l0p
View 4l0p on RCSB PDB site
Description: Structure of the human EphA3 receptor ligand binding domain complexed with ephrin-A5
Class: transferase/transferase receptor
Keywords: beta-sandwich, Receptor Tyrosine Kinase, ephrin binding, TRANSFERASE-TRANSFERASE RECEPTOR complex
Deposited on
2013-05-31, released
2014-06-11
The last revision prior to the SCOPe 2.08 freeze date was dated
2020-07-29, with a file datestamp of
2020-07-04.
Experiment type: XRAY
Resolution: 2.26 Å
R-factor: N/A
AEROSPACI score: 0.32
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Ephrin type-A receptor 3
Species: Homo sapiens [TaxId:9606]
Gene: EPHA3, EPHA3_HUMAN, ETK, ETK1, HEK, TYRO4
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4l0pa1, d4l0pa2 - Chain 'B':
Compound: Ephrin-A5
Species: Homo sapiens [TaxId:9606]
Gene: EFNA5, EFNA5_HUMAN, EPLG7, LERK7
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4l0pb_ - Heterogens: SO4, CA, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4l0pA (A:)
gsgevnlldsktiqgelgwisypshgweeisgvdehytpirtyqvcnvmdhsqnnwlrtn
wvprnsaqkiyvelkftlrdcnsiplvlgtcketfnlyymesdddhgvkfrehqftkidt
iaadesftqmdlgdrilklnteirevgpvnkkgfylafqdvgacvalvsvrvyfkk
Sequence, based on observed residues (ATOM records): (download)
>4l0pA (A:)
sgevnlldsktiqgelgwisypshgweeisgvdehytpirtyqvcnvmdhsqnnwlrtnw
vprnsaqkiyvelkftlrdcnsiplvlgtcketfnlyymesdddhgvkfrehqftkidti
aadesftqmdlgdrilklnteirevgpvnkkgfylafqdvgacvalvsvrvyfkk
- Chain 'B':
Sequence, based on SEQRES records: (download)
>4l0pB (B:)
gsgavadryavywnssnprfqrgdyhidvcindyldvfcphyedsvpedkteryvlymvn
fdgysacdhtskgfkrwecnrphspngplkfsekfqlftpfslgfefrpgreyfyissai
pdngrrsclklkvfvrptnscmk
Sequence, based on observed residues (ATOM records): (download)
>4l0pB (B:)
avadryavywnssnprfqrgdyhidvcindyldvfcphyedsvpedkteryvlymvnfdg
ysacdhtskgfkrwecnrphspngplkfsekfqlftpfslgfefrpgreyfyissaipdn
grrsclklkvfvrptnscm