PDB entry 4kzm

View 4kzm on RCSB PDB site
Description: Crystal Structure of TR3 LBD S553A Mutant
Class: transcription
Keywords: orphan nuclear receptor, transcription
Deposited on 2013-05-30, released 2013-12-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-25, with a file datestamp of 2019-12-20.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nuclear receptor subfamily 4 group A member 1
    Species: Homo sapiens [TaxId:9606]
    Gene: GFRP1, HMR, NAK1, NR4A1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22736 (Start-248)
      • engineered mutation (203)
    Domains in SCOPe 2.08: d4kzma_
  • Chain 'B':
    Compound: Nuclear receptor subfamily 4 group A member 1
    Species: Homo sapiens [TaxId:9606]
    Gene: GFRP1, HMR, NAK1, NR4A1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22736 (Start-248)
      • engineered mutation (203)
    Domains in SCOPe 2.08: d4kzmb_
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4kzmA (A:)
mskpkqppdaspanlltslvrahldsgpstakldyskfqelvlphfgkedagdvqqfydl
lsgslevirkwaekipgfaelspadqdlllesaflelfilrlayrskpgegklifcsglv
lhrlqcargfgdwidsilafsrslhsllvdvpafaclsalvlitdrhglqeprrveelqn
riasclkehvaavagepqpasclarllgklpelrtlctqglqrifylkledlvppppiid
kifmdtlpflehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4kzmA (A:)
anlltslvrahldsgpstakldyskfqelvlphfgkedagdvqqfydllsgslevirkwa
ekipgfaelspadqdlllesaflelfilrlayrskpgegklifcsglvlhrlqcargfgd
widsilafsrslhsllvdvpafaclsalvlitdrhglqeprrveelqnriasclkehvaa
vagasclarllgklpelrtlctqglqrifylkledlvppppiidkifmdtlpf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4kzmB (B:)
mskpkqppdaspanlltslvrahldsgpstakldyskfqelvlphfgkedagdvqqfydl
lsgslevirkwaekipgfaelspadqdlllesaflelfilrlayrskpgegklifcsglv
lhrlqcargfgdwidsilafsrslhsllvdvpafaclsalvlitdrhglqeprrveelqn
riasclkehvaavagepqpasclarllgklpelrtlctqglqrifylkledlvppppiid
kifmdtlpflehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4kzmB (B:)
panlltslvrahldsgpstakldyskfqelvlpkedagdvqqfydllsgslevirkwaek
ipgfaelspadqdlllesaflelfilrlayrskpgegklifcsglvlhrlqcargfgdwi
dsilafsrslhsllvdvpafaclsalvlitdrhglqeprrveelqnriasclkehvaava
asclarllgklpelrtlctqglqrifylkledlvppppiidkifmdtlpf