PDB entry 4kxt

View 4kxt on RCSB PDB site
Description: Structure of human ARGONAUTE1 in complex with guide RNA
Class: hydrolase/RNA
Keywords: RNase H fold, nuclease, RNA, HYDROLASE-RNA complex
Deposited on 2013-05-28, released 2013-07-31
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-07-31, with a file datestamp of 2013-07-26.
Experiment type: XRAY
Resolution: 2.29 Å
R-factor: 0.177
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protein argonaute-1
    Species: Homo sapiens [TaxId:9606]
    Gene: EIF2C1, AGO1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4kxta1, d4kxta2, d4kxta3
  • Chain 'B':
    Compound: RNA
    Species: Spodoptera frugiperda [TaxId:7108]
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4kxtA (A:)
gamgsmeagpsgaaagaylpplqqvfqaprrpgigtvgkpikllanyfevdipkidvyhy
evdikpdkcprrvnrevveymvqhfkpqifgdrkpvydgkkniytvtalpignervdfev
tipgegkdrifkvsikwlaivswrmlhealvsgqipvplesvqaldvamrhlasmrytpv
grsffsppegyyhplgggrevwfgfhqsvrpamwkmmlnidvsatafykaqpviefmcev
ldirnideqpkpltdsqrvrftkeikglkvevthcgqmkrkyrvcnvtrrpashqtfplq
lesgqtvectvaqyfkqkynlqlkyphlpclqvgqeqkhtylplevcnivagqrcikklt
dnqtstmikatarsapdrqeeisrlmknasynldpyiqefgikvkddmtevtgrvlpapi
lqyggrnraiatpnqgvwdmrgkqfyngieikvwaiacfapqkqcreevlknftdqlrki
skdagmpiqgqpcfckyaqgadsvepmfrhlkntysglqliivilpgktpvyaevkrvgd
tllgmatqcvqvknvvktspqtlsnlclkinvklgginnilvphqrsavfqqpviflgad
vthppagdgkkpsitavvgsmdahpsrycatvrvqrprqeiiedlsymvrelliqfykst
rfkptriifyrdgvpegqlpqilhyellairdaciklekdyqpgityivvqkrhhtrlfc
adknerigksgnipagttvdtnithpfefdfylcshagiqgtsrpshyyvlwddnrftad
elqiltyqlchtyvrctrsvsipapayyarlvafraryhlvdkehdsgegshisgqsngr
dpqalakavqvhqdtlrtmyfa

    Sequence, based on observed residues (ATOM records): (download) 
    >4kxtA (A:)
qaprrpgigtvgkpikllanyfevdipkidvyhyevdikpdkcprrvnrevveymvqhfk
pqifgdrkpvydgkkniytvtalpignervdkvsikwlaivswrmlhealvsgqipvple
svqaldvamrhlasmrytpvgrsffsppegyyhplgggrevwfgfhqsvrpamwkmmlni
dvsatafykaqpviefmcevldirnideqpkpltdsqrvrftkeikglkvevthcgqmkr
kyrvcnvtrrpashqtfplqlesgqtvectvaqyfkqkynlqlkyphlpclqvgqeqkht
ylplevcnivagqrcikkltdnqtstmikatarsapdrqeeisrlmknasynldpyiqef
gikvkddmtevtgrvlpapilqyggrnraiatpnqgvwdmrgkqfyngieikvwaiacfa
pqkqcreevlknftdqlrkiskdagmpiqgqpcfckyaqgadsvepmfrhlkntysglql
iivilpgktpvyaevkrvgdtllgmatqcvqvknvvktspqtlsnlclkinvklgginni
lvphqrsavfqqpviflgadvthppagdgkkpsitavvgsmdahpsrycatvrvqrprqe
iiedlsymvrelliqfykstrfkptriifyrdgvpegqlpqilhyellairdaciklekd
yqpgityivvqkrhhtrlfcadknerigksgnipagttvdtnithpfefdfylcshagiq
gtsrpshyyvlwddnrftadelqiltyqlchtyvrctrsvsipapayyarlvafraryhl
vdkrdpqalakavqvhqdtlrtmyfa

  • Chain 'B':
    No sequence available.