PDB entry 4kml
View 4kml on RCSB PDB site
Description: Probing the N-terminal beta-sheet conversion in the crystal structure of the full-length human prion protein bound to a Nanobody
Class: membrane protein/protein binding
Keywords: Prion-like fold, antibody, nanobody, MEMBRANE PROTEIN-PROTEIN BINDING complex
Deposited on
2013-05-08, released
2014-02-19
The last revision prior to the SCOPe 2.08 freeze date was dated
2018-01-24, with a file datestamp of
2018-01-19.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: N/A
AEROSPACI score: 0.49
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: major prion protein
Species: Homo sapiens [TaxId:9606]
Gene: PRIP, PRNP, PRP
Database cross-references and differences (RAF-indexed):
- Chain 'B':
Compound: Nanobody
Species: LAMA GLAMA [TaxId:9844]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4kmlb1, d4kmlb2 - Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
No sequence available.
- Chain 'B':
Sequence, based on SEQRES records: (download)
>4kmlB (B:)
avqlqesggglvqpggslrlscaasgrtfssynmgwfrqapgkgrefvasitssgdksdy
tdsvkgrftisrdnakntmylqmnnlkpedtatyycarglgiyiirarggydhwgqgtqv
tvsshhhhhh
Sequence, based on observed residues (ATOM records): (download)
>4kmlB (B:)
avqlqesggglvqpggslrlscaasgrtfssynmgwfrqapgkgrefvasitssgdksdy
tdsvkgrftisrdnakntmylqmnnlkpedtatyycarglgiyiirarggydhwgqgtqv
tvs