PDB entry 4kln

View 4kln on RCSB PDB site
Description: Structure of p97 N-D1 A232E mutant in complex with ATPgS
Class: hydrolase
Keywords: Transport protein, HYDROLASE
Deposited on 2013-05-07, released 2013-11-13
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-01-08, with a file datestamp of 2014-01-03.
Experiment type: XRAY
Resolution: 2.62 Å
R-factor: 0.275
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transitional endoplasmic reticulum ATPase
    Species: Homo sapiens [TaxId:9606]
    Gene: P97, VCP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P55072
      • engineered mutation (231)
    Domains in SCOPe 2.07: d4klna1, d4klna2, d4klna3
  • Chain 'B':
    Compound: Transitional endoplasmic reticulum ATPase
    Species: Homo sapiens [TaxId:9606]
    Gene: P97, VCP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P55072
      • engineered mutation (231)
    Domains in SCOPe 2.07: d4klnb1, d4klnb2, d4klnb3
  • Chain 'C':
    Compound: Transitional endoplasmic reticulum ATPase
    Species: Homo sapiens [TaxId:9606]
    Gene: P97, VCP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P55072
      • engineered mutation (231)
    Domains in SCOPe 2.07: d4klnc1, d4klnc2, d4klnc3
  • Chain 'D':
    Compound: Transitional endoplasmic reticulum ATPase
    Species: Homo sapiens [TaxId:9606]
    Gene: P97, VCP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P55072
      • engineered mutation (231)
    Domains in SCOPe 2.07: d4klnd1, d4klnd2, d4klnd3
  • Chain 'E':
    Compound: Transitional endoplasmic reticulum ATPase
    Species: Homo sapiens [TaxId:9606]
    Gene: P97, VCP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P55072
      • engineered mutation (231)
    Domains in SCOPe 2.07: d4klne1, d4klne2, d4klne3
  • Chain 'F':
    Compound: Transitional endoplasmic reticulum ATPase
    Species: Homo sapiens [TaxId:9606]
    Gene: P97, VCP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P55072
      • engineered mutation (231)
    Domains in SCOPe 2.07: d4klnf1, d4klnf2, d4klnf3
  • Heterogens: AGS, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4klnA (A:)
masgadskgddlstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllk
gkkrreavcivlsddtcsdekirmnrvvrnnlrvrlgdvisiqpcpdvkygkrihvlpid
dtvegitgnlfevylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdt
vihcegepikredeeeslnevgyddiggcrkqlaqikemvelplrhpalfkeigvkpprg
illygppgtgktliaravanetgaffflingpeimsklagesesnlrkafeeaeknapai
ifideldaiapkrekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrf
grfdrevdigipdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaal
qairkkmdlidledetidaevmnslavtmddfrwalsqsnpsalretvvevpqvtwedig
grshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4klnA (A:)
lstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllkgkkrreavciv
lsddtcsdekirmnrvvrnnlrvrlgdvisiqpcpdvkygkrihvlpiddtvegitgnlf
evylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdtvihcegepikr
edeeeslnevgyddiggcrkqlaqikemvelplrhpalfkeigvkpprgillygppgtgk
tliaravanetgaffflingpeimsklagesesnlrkafeeaeknapaiifideldaiap
krekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrfgrfdrevdigi
pdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaalqairkkmdlid
ledetidaevmnslavtmddfrwalsqsnps

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4klnB (B:)
masgadskgddlstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllk
gkkrreavcivlsddtcsdekirmnrvvrnnlrvrlgdvisiqpcpdvkygkrihvlpid
dtvegitgnlfevylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdt
vihcegepikredeeeslnevgyddiggcrkqlaqikemvelplrhpalfkeigvkpprg
illygppgtgktliaravanetgaffflingpeimsklagesesnlrkafeeaeknapai
ifideldaiapkrekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrf
grfdrevdigipdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaal
qairkkmdlidledetidaevmnslavtmddfrwalsqsnpsalretvvevpqvtwedig
grshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4klnB (B:)
lstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllkgkkrreavciv
lsddtcsdekirmnrvvrnnlrvrlgdvisiqpcpdvkygkrihvlpiddtvegitgnlf
evylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdtvihcegepikr
edeeeslnevgyddiggcrkqlaqikemvelplrhpalfkeigvkpprgillygppgtgk
tliaravanetgaffflingpeimsklagesesnlrkafeeaeknapaiifideldaiap
krekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrfgrfdrevdigi
pdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaalqairkkmdlid
ledetidaevmnslavtmddfrwalsqsnps

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4klnC (C:)
masgadskgddlstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllk
gkkrreavcivlsddtcsdekirmnrvvrnnlrvrlgdvisiqpcpdvkygkrihvlpid
dtvegitgnlfevylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdt
vihcegepikredeeeslnevgyddiggcrkqlaqikemvelplrhpalfkeigvkpprg
illygppgtgktliaravanetgaffflingpeimsklagesesnlrkafeeaeknapai
ifideldaiapkrekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrf
grfdrevdigipdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaal
qairkkmdlidledetidaevmnslavtmddfrwalsqsnpsalretvvevpqvtwedig
grshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4klnC (C:)
lstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllkgkkrreavciv
lsddtcsdekirmnrvvrnnlrvrlgdvisiqpcpdvkygkrihvlpiddtvegitgnlf
evylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdtvihcegepikr
edeeeslnevgyddiggcrkqlaqikemvelplrhpalfkeigvkpprgillygppgtgk
tliaravanetgaffflingpeimsklagesesnlrkafeeaeknapaiifideldaiap
krekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrfgrfdrevdigi
pdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaalqairkkmdlid
ledetidaevmnslavtmddfrwalsqsnps

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4klnD (D:)
masgadskgddlstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllk
gkkrreavcivlsddtcsdekirmnrvvrnnlrvrlgdvisiqpcpdvkygkrihvlpid
dtvegitgnlfevylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdt
vihcegepikredeeeslnevgyddiggcrkqlaqikemvelplrhpalfkeigvkpprg
illygppgtgktliaravanetgaffflingpeimsklagesesnlrkafeeaeknapai
ifideldaiapkrekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrf
grfdrevdigipdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaal
qairkkmdlidledetidaevmnslavtmddfrwalsqsnpsalretvvevpqvtwedig
grshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4klnD (D:)
lstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllkgkkrreavciv
lsddtcsdekirmnrvvrnnlrvrlgdvisiqpcpdvkygkrihvlpiddtvegitgnlf
evylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdtvihcegepikr
edeeeslnevgyddiggcrkqlaqikemvelplrhpalfkeigvkpprgillygppgtgk
tliaravanetgaffflingpeimsklagesesnlrkafeeaeknapaiifideldaiap
krekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrfgrfdrevdigi
pdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaalqairkkmdlid
ledetidaevmnslavtmddfrwalsqsnps

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4klnE (E:)
masgadskgddlstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllk
gkkrreavcivlsddtcsdekirmnrvvrnnlrvrlgdvisiqpcpdvkygkrihvlpid
dtvegitgnlfevylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdt
vihcegepikredeeeslnevgyddiggcrkqlaqikemvelplrhpalfkeigvkpprg
illygppgtgktliaravanetgaffflingpeimsklagesesnlrkafeeaeknapai
ifideldaiapkrekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrf
grfdrevdigipdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaal
qairkkmdlidledetidaevmnslavtmddfrwalsqsnpsalretvvevpqvtwedig
grshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4klnE (E:)
lstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllkgkkrreavciv
lsddtcsdekirmnrvvrnnlrvrlgdvisiqpcpdvkygkrihvlpiddtvegitgnlf
evylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdtvihcegepikr
edeeeslnevgyddiggcrkqlaqikemvelplrhpalfkeigvkpprgillygppgtgk
tliaravanetgaffflingpeimsklagesesnlrkafeeaeknapaiifideldaiap
krekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrfgrfdrevdigi
pdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaalqairkkmdlid
ledetidaevmnslavtmddfrwalsqsnps

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >4klnF (F:)
masgadskgddlstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllk
gkkrreavcivlsddtcsdekirmnrvvrnnlrvrlgdvisiqpcpdvkygkrihvlpid
dtvegitgnlfevylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdt
vihcegepikredeeeslnevgyddiggcrkqlaqikemvelplrhpalfkeigvkpprg
illygppgtgktliaravanetgaffflingpeimsklagesesnlrkafeeaeknapai
ifideldaiapkrekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrf
grfdrevdigipdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaal
qairkkmdlidledetidaevmnslavtmddfrwalsqsnpsalretvvevpqvtwedig
grshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4klnF (F:)
lstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllkgkkrreavciv
lsddtcsdekirmnrvvrnnlrvrlgdvisiqpcpdvkygkrihvlpiddtvegitgnlf
evylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdtvihcegepikr
edeeeslnevgyddiggcrkqlaqikemvelplrhpalfkeigvkpprgillygppgtgk
tliaravanetgaffflingpeimsklagesesnlrkafeeaeknapaiifideldaiap
krekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrfgrfdrevdigi
pdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaalqairkkmdlid
ledetidaevmnslavtmddfrwalsqsnps