PDB entry 4kkh

View 4kkh on RCSB PDB site
Description: The crystal structure of inhibitor-bound JNK3
Class: transferase/transferase inhibitor
Keywords: kinase domain, kinase, c-jun, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2013-05-06, released 2014-05-21
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-05-21, with a file datestamp of 2014-05-16.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.232
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 10
    Species: Homo sapiens [TaxId:9606]
    Gene: MAPK10, JNK3, JNK3A, PRKM10, SAPK1B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4kkha_
  • Heterogens: 1RQ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4kkhA (A:)
mgskskvdnqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikklsr
pfqnqthakrayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqvi
qmeldhermsyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglartagts
fmmtpyvvtryyrapevilgmgykenvdiwsvgcimgemvrhkilfpgrdyidqwnkvie
qlgtpcpefmkklqptvrnyvenrpkyagltfpklfpdslfpadsehnklkasqardlls
kmlvidpakrisvddalqhpyinvwydpaeveapppqiydkqlderehtieewkeliyke
vmnse

    Sequence, based on observed residues (ATOM records): (download) 
    >4kkhA (A:)
dnqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikklsrpfqnqth
akrayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldhe
rmsyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglartasfmmtpyvvt
ryyrapevilgmgykenvdiwsvgcimgemvrhkilfpgrdyidqwnkvieqlgtpcpef
mkklqptvrnyvenrpkyagltfpklfpdslfpadsehnklkasqardllskmlvidpak
risvddalqhpyinvwydpaeveapppqkqlderehtieewkeliykevmn