PDB entry 4kgz

View 4kgz on RCSB PDB site
Description: The R state structure of E. coli ATCase with UTP and Magnesium bound
Class: transferase
Keywords: pyrimidine nucleotide biosynthesis, feedback inhibition, competing pathway product activation, allostery, TRANSFERASE
Deposited on 2013-04-29, released 2013-11-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: aspartate carbamoyltransferase
    Species: Escherichia coli [TaxId:595495]
    Gene: pyrB, EKO11_4066, KO11_22860
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4kgza1, d4kgza2
  • Chain 'B':
    Compound: Aspartate carbamoyltransferase regulatory chain
    Species: Escherichia coli [TaxId:595495]
    Gene: pyrI, EKO11_4067, KO11_22855
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4kgzb1, d4kgzb2
  • Chain 'C':
    Compound: aspartate carbamoyltransferase
    Species: Escherichia coli [TaxId:595495]
    Gene: pyrB, EKO11_4066, KO11_22860
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4kgzc1, d4kgzc2
  • Chain 'D':
    Compound: Aspartate carbamoyltransferase regulatory chain
    Species: Escherichia coli [TaxId:595495]
    Gene: pyrI, EKO11_4067, KO11_22855
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4kgzd1, d4kgzd2
  • Heterogens: PAL, ZN, UTP, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4kgzA (A:)
anplyqkhiisindlsrddlnlvlataaklkanpqpellkhkviascffeastrtrlsfe
tsmhrlgasvvgfsdsantslgkkgetladtisvistyvdaivmrhpqegaarlatefsg
nvpvlnagdgsnqhptqtlldlftiqetqgrldnlhvamvgdlkygrtvhsltqalakfd
gnrfyfiapdalampqyildmldekgiawslhssieevmaevdilymtrvqkerldpsey
anvkaqfvlrasdlhnakanmkvlhplprvdeiatdvdktphawyfqqagngifarqall
alvlnrdlvl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4kgzB (B:)
mthdnklqveaikrgtvidhipaqigfkllslfkltetdqritiglnlpsgemgrkdlik
ientflsedqvdqlalyapqatvnridnyevvgksrpslperidnvlvcpnsncishaep
vsssfavrkrandialkckycekefshnvvlan

    Sequence, based on observed residues (ATOM records): (download) 
    >4kgzB (B:)
eaikrgtvidhipaqigfkllslfkltetdqritiglnlpsgemgrkdlikientflsed
qvdqlalyapqatvnridnyevvgksrpslperidnvlvcpnsncishaepvsssfavrk
randialkckycekefshnvvlan

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4kgzC (C:)
anplyqkhiisindlsrddlnlvlataaklkanpqpellkhkviascffeastrtrlsfe
tsmhrlgasvvgfsdsantslgkkgetladtisvistyvdaivmrhpqegaarlatefsg
nvpvlnagdgsnqhptqtlldlftiqetqgrldnlhvamvgdlkygrtvhsltqalakfd
gnrfyfiapdalampqyildmldekgiawslhssieevmaevdilymtrvqkerldpsey
anvkaqfvlrasdlhnakanmkvlhplprvdeiatdvdktphawyfqqagngifarqall
alvlnrdlvl

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4kgzD (D:)
mthdnklqveaikrgtvidhipaqigfkllslfkltetdqritiglnlpsgemgrkdlik
ientflsedqvdqlalyapqatvnridnyevvgksrpslperidnvlvcpnsncishaep
vsssfavrkrandialkckycekefshnvvlan

    Sequence, based on observed residues (ATOM records): (download) 
    >4kgzD (D:)
aikrgtvidhipaqigfkllslfkltetdqritiglnlpsgemgrkdlikientflsedq
vdqlalyapqatvnridnyevvgksrpslperidnvlvcpnsncishaepvsssfavrkr
andialkckycekefshnvvlan