PDB entry 4kax

View 4kax on RCSB PDB site
Description: Crystal structure of the Grp1 PH domain in complex with Arf6-GTP
Class: protein binding/signaling protein
Keywords: PH domain, Phosphoinositides, PROTEIN BINDING-SIGNALING PROTEIN complex
Deposited on 2013-04-23, released 2013-08-14
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ADP-ribosylation factor 6
    Species: Homo sapiens [TaxId:9606]
    Gene: ARF6
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62330 (8-167)
      • expression tag (6-7)
      • engineered mutation (61)
      • expression tag (168)
    Domains in SCOPe 2.07: d4kaxa1, d4kaxa2, d4kaxa3
  • Chain 'B':
    Compound: Cytohesin-3
    Species: Homo sapiens [TaxId:9606]
    Gene: CYTH3, ARNO3, GRP1, PSCD3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4kaxb_
  • Heterogens: GTP, MG, CIT, GOL, K, 4IP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4kaxA (A:)
    hhhhhhgsmrilmlgldaagkttilyklklgqsvttiptvgfnvetvtyknvkfnvwdvg
    gldkirplwrhyytgtqglifvvdcadrdridearqelhriindremrdaiilifankqd
    lpdamkpheiqeklgltrirdrnwyvqpscatsgdglyegltwltsnyn
    

    Sequence, based on observed residues (ATOM records): (download)
    >4kaxA (A:)
    gsmrilmlgldaagkttilyklklgqsvttiptvgfnvetvtyknvkfnvwdvggldkir
    plwrhyytgtqglifvvdcadrdridearqelhriindremrdaiilifankqdlpdamk
    pheiqeklgltrirdrnwyvqpscatsgdglyegltwltsnyn
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4kaxB (B:)
    hhhhhhgspfkipeddgndlthtffnpdregwllklggrvktwkrrwfiltdnclyyfey
    ttdkeprgiiplenlsirevedprkpncfelynpshkgqvikackteadgrvvegnhvvy
    risapspeekeewmksikasisrdpfydmlatrkrriankk
    

    Sequence, based on observed residues (ATOM records): (download)
    >4kaxB (B:)
    gndlthtffnpdregwllklggrvktwkrrwfiltdnclyyfeyttdkeprgiiplenls
    irevedprkpncfelynpshkgqvikackteadgrvvegnhvvyrisapspeekeewmks
    ikasisrdpfydmlatrkrrian