PDB entry 4k77

View 4k77 on RCSB PDB site
Description: JAK1 kinase (JH1 domain) in complex with compound 6
Class: transferase/transferase inhibitor
Keywords: protein kinase, phosphotransfer, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2013-04-16, released 2013-10-02
The last revision prior to the SCOPe 2.03 freeze date was dated 2013-10-23, with a file datestamp of 2013-10-18.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.193
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein kinase JAK1
    Species: Homo sapiens [TaxId:9606]
    Gene: JAK1, JAK1A, JAK1B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d4k77a_
  • Chain 'B':
    Compound: Tyrosine-protein kinase JAK1
    Species: Homo sapiens [TaxId:9606]
    Gene: JAK1, JAK1A, JAK1B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d4k77b_
  • Heterogens: 1Q4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4k77A (A:)
gdivsekkpatevdpthfekrflkrirdlgeghfgkvelcrydpegdntgeqvavkslkp
esggnhiadlkkeieilrnlyhenivkykgictedggngiklimeflpsgslkeylpknk
nkinlkqqlkyavqickgmdylgsrqyvhrdlaarnvlvesehqvkigdfgltkaietdk
eyytvkddrdspvfwyapeclmqskfyiasdvwsfgvtlhelltycdsdsspmalflkmi
gpthgqmtvtrlvntlkegkrlpcppncpdevyqlmrkcwefqpsnrtsfqnliegfeal
lk

    Sequence, based on observed residues (ATOM records): (download) 
    >4k77A (A:)
evdpthfekrflkrirdlgeghfgkvelcrydpegdntgeqvavkslkpgnhiadlkkei
eilrnlyhenivkykgictegiklimeflpsgslkeylpknknkinlkqqlkyavqickg
mdylgsrqyvhrdlaarnvlvesehqvkigdfgltkaietdkeyytvkddrdspvfwyap
eclmqskfyiasdvwsfgvtlhelltycdsdsspmalflkmigpthgqmtvtrlvntlke
gkrlpcppncpdevyqlmrkcwefqpsnrtsfqnliegfeallk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4k77B (B:)
gdivsekkpatevdpthfekrflkrirdlgeghfgkvelcrydpegdntgeqvavkslkp
esggnhiadlkkeieilrnlyhenivkykgictedggngiklimeflpsgslkeylpknk
nkinlkqqlkyavqickgmdylgsrqyvhrdlaarnvlvesehqvkigdfgltkaietdk
eyytvkddrdspvfwyapeclmqskfyiasdvwsfgvtlhelltycdsdsspmalflkmi
gpthgqmtvtrlvntlkegkrlpcppncpdevyqlmrkcwefqpsnrtsfqnliegfeal
lk

    Sequence, based on observed residues (ATOM records): (download) 
    >4k77B (B:)
vdpthfekrflkrirdlgeghfgkvelcrydpegdntgeqvavkslkpnhiadlkkeiei
lrnlyhenivkykgictngiklimeflpsgslkeylpknknkinlkqqlkyavqickgmd
ylgsrqyvhrdlaarnvlvesehqvkigdfgltkaietdkeyytvkddrdspvfwyapec
lmqskfyiasdvwsfgvtlhelltycdsdsspmalflkmigpthgqmtvtrlvntlkegk
rlpcppncpdevyqlmrkcwefqpsnrtsfqnliegfeallk