PDB entry 4k6u

View 4k6u on RCSB PDB site
Description: Crystal structure of Ad37 fiber knob in complex with trivalent sialic acid inhibitor ME0386
Class: viral protein
Keywords: adenovirus, fiber knob, protein carbohydrate interaction, carbohydrate mimic, multivalent ligand, VIRAL PROTEIN
Deposited on 2013-04-16, released 2014-10-22
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-09-09, with a file datestamp of 2015-09-04.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: fiber protein
    Species: HUMAN ADENOVIRUS 37 [TaxId:52275]
    Gene: L5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4k6ua_
  • Chain 'B':
    Compound: fiber protein
    Species: HUMAN ADENOVIRUS 37 [TaxId:52275]
    Gene: L5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4k6ub_
  • Chain 'C':
    Compound: fiber protein
    Species: HUMAN ADENOVIRUS 37 [TaxId:52275]
    Gene: L5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4k6uc_
  • Heterogens: ZN, SIA, 1P4, ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4k6uA (A:)
gamgswnpkydtrtlwttpdtspnctiaqdkdskltlvltkcgsqilanvslivvagkyh
iinnktnpkiksftikllfnkngvlldnsnlgkaywnfrsgnsnvstayekaigfmpnlv
aypkpsnskkyardivygtiylggkpdqpavikttfnqetgceysitfnfswsktyenve
fettsftfsyiaqe

    Sequence, based on observed residues (ATOM records): (download) 
    >4k6uA (A:)
dtrtlwttpdtspnctiaqdkdskltlvltkcgsqilanvslivvagkyhiinnktnpki
ksftikllfnkngvlldnsnlgkaywnfrsgnsnvstayekaigfmpnlvaypkpsnskk
yardivygtiylggkpdqpavikttfnqetgceysitfnfswsktyenvefettsftfsy
iaqe

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4k6uB (B:)
gamgswnpkydtrtlwttpdtspnctiaqdkdskltlvltkcgsqilanvslivvagkyh
iinnktnpkiksftikllfnkngvlldnsnlgkaywnfrsgnsnvstayekaigfmpnlv
aypkpsnskkyardivygtiylggkpdqpavikttfnqetgceysitfnfswsktyenve
fettsftfsyiaqe

    Sequence, based on observed residues (ATOM records): (download) 
    >4k6uB (B:)
pkydtrtlwttpdtspnctiaqdkdskltlvltkcgsqilanvslivvagkyhiinnktn
pkiksftikllfnkngvlldnsnlgkaywnfrsgnsnvstayekaigfmpnlvaypkpsn
skkyardivygtiylggkpdqpavikttfnqetgceysitfnfswsktyenvefettsft
fsyiaqe

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4k6uC (C:)
gamgswnpkydtrtlwttpdtspnctiaqdkdskltlvltkcgsqilanvslivvagkyh
iinnktnpkiksftikllfnkngvlldnsnlgkaywnfrsgnsnvstayekaigfmpnlv
aypkpsnskkyardivygtiylggkpdqpavikttfnqetgceysitfnfswsktyenve
fettsftfsyiaqe

    Sequence, based on observed residues (ATOM records): (download) 
    >4k6uC (C:)
trtlwttpdtspnctiaqdkdskltlvltkcgsqilanvslivvagkyhiinnktnpkik
sftikllfnkngvlldnsnlgkaywnfrsgnsnvstayekaigfmpnlvaypkpsnskky
ardivygtiylggkpdqpavikttfnqetgceysitfnfswsktyenvefettsftfsyi
aqe