PDB entry 4k6t

View 4k6t on RCSB PDB site
Description: Crystal structure of Ad37 fiber knob in complex with trivalent sialic acid inhibitor ME0385
Class: viral protein
Keywords: adenovirus, fiber knob, protein carbohydrate interaction, sialic acid, carbohydrate mimic, multivalent ligand, VIRAL PROTEIN
Deposited on 2013-04-16, released 2014-10-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: fiber protein
    Species: HUMAN ADENOVIRUS 37 [TaxId:52275]
    Gene: L5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4k6ta_
  • Chain 'B':
    Compound: fiber protein
    Species: HUMAN ADENOVIRUS 37 [TaxId:52275]
    Gene: L5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4k6tb_
  • Chain 'C':
    Compound: fiber protein
    Species: HUMAN ADENOVIRUS 37 [TaxId:52275]
    Gene: L5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4k6tc_
  • Chain 'E':
    Compound: fiber protein
    Species: HUMAN ADENOVIRUS 37 [TaxId:52275]
    Gene: L5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4k6te_
  • Chain 'F':
    Compound: fiber protein
    Species: HUMAN ADENOVIRUS 37 [TaxId:52275]
    Gene: L5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4k6tf_
  • Chain 'G':
    Compound: fiber protein
    Species: HUMAN ADENOVIRUS 37 [TaxId:52275]
    Gene: L5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4k6tg_
  • Heterogens: SIA, ZN, ACT, EDO, CL, 1P0, MG, GOL, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4k6tA (A:)
gamgswnpkydtrtlwttpdtspnctiaqdkdskltlvltkcgsqilanvslivvagkyh
iinnktnpkiksftikllfnkngvlldnsnlgkaywnfrsgnsnvstayekaigfmpnlv
aypkpsnskkyardivygtiylggkpdqpavikttfnqetgceysitfnfswsktyenve
fettsftfsyiaqe

    Sequence, based on observed residues (ATOM records): (download) 
    >4k6tA (A:)
kydtrtlwttpdtspnctiaqdkdskltlvltkcgsqilanvslivvagkyhiinnktnp
kiksftikllfnkngvlldnsnlgkaywnfrsgnsnvstayekaigfmpnlvaypkpsns
kkyardivygtiylggkpdqpavikttfnqetgceysitfnfswsktyenvefettsftf
syiaqe

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4k6tB (B:)
gamgswnpkydtrtlwttpdtspnctiaqdkdskltlvltkcgsqilanvslivvagkyh
iinnktnpkiksftikllfnkngvlldnsnlgkaywnfrsgnsnvstayekaigfmpnlv
aypkpsnskkyardivygtiylggkpdqpavikttfnqetgceysitfnfswsktyenve
fettsftfsyiaqe

    Sequence, based on observed residues (ATOM records): (download) 
    >4k6tB (B:)
kydtrtlwttpdtspnctiaqdkdskltlvltkcgsqilanvslivvagkyhiinnktnp
kiksftikllfnkngvlldnsnlgkaywnfrsgnsnvstayekaigfmpnlvaypkpsns
kkyardivygtiylggkpdqpavikttfnqetgceysitfnfswsktyenvefettsftf
syiaqe

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4k6tC (C:)
gamgswnpkydtrtlwttpdtspnctiaqdkdskltlvltkcgsqilanvslivvagkyh
iinnktnpkiksftikllfnkngvlldnsnlgkaywnfrsgnsnvstayekaigfmpnlv
aypkpsnskkyardivygtiylggkpdqpavikttfnqetgceysitfnfswsktyenve
fettsftfsyiaqe

    Sequence, based on observed residues (ATOM records): (download) 
    >4k6tC (C:)
rtlwttpdtspnctiaqdkdskltlvltkcgsqilanvslivvagkyhiinnktnpkiks
ftikllfnkngvlldnsnlgkaywnfrsgnsnvstayekaigfmpnlvaypkpsnskkya
rdivygtiylggkpdqpavikttfnqetgceysitfnfswsktyenvefettsftfsyia
qe

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4k6tE (E:)
gamgswnpkydtrtlwttpdtspnctiaqdkdskltlvltkcgsqilanvslivvagkyh
iinnktnpkiksftikllfnkngvlldnsnlgkaywnfrsgnsnvstayekaigfmpnlv
aypkpsnskkyardivygtiylggkpdqpavikttfnqetgceysitfnfswsktyenve
fettsftfsyiaqe

    Sequence, based on observed residues (ATOM records): (download) 
    >4k6tE (E:)
ydtrtlwttpdtspnctiaqdkdskltlvltkcgsqilanvslivvagkyhiinnktnpk
iksftikllfnkngvlldnsnlgkaywnfrsgnsnvstayekaigfmpnlvaypkpsnsk
kyardivygtiylggkpdqpavikttfnqetgceysitfnfswsktyenvefettsftfs
yiaqe

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >4k6tF (F:)
gamgswnpkydtrtlwttpdtspnctiaqdkdskltlvltkcgsqilanvslivvagkyh
iinnktnpkiksftikllfnkngvlldnsnlgkaywnfrsgnsnvstayekaigfmpnlv
aypkpsnskkyardivygtiylggkpdqpavikttfnqetgceysitfnfswsktyenve
fettsftfsyiaqe

    Sequence, based on observed residues (ATOM records): (download) 
    >4k6tF (F:)
kydtrtlwttpdtspnctiaqdkdskltlvltkcgsqilanvslivvagkyhiinnktnp
kiksftikllfnkngvlldnsnlgkaywnfrsgnsnvstayekaigfmpnlvaypkpsns
kkyardivygtiylggkpdqpavikttfnqetgceysitfnfswsktyenvefettsftf
syiaqe

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >4k6tG (G:)
gamgswnpkydtrtlwttpdtspnctiaqdkdskltlvltkcgsqilanvslivvagkyh
iinnktnpkiksftikllfnkngvlldnsnlgkaywnfrsgnsnvstayekaigfmpnlv
aypkpsnskkyardivygtiylggkpdqpavikttfnqetgceysitfnfswsktyenve
fettsftfsyiaqe

    Sequence, based on observed residues (ATOM records): (download) 
    >4k6tG (G:)
ydtrtlwttpdtspnctiaqdkdskltlvltkcgsqilanvslivvagkyhiinnktnpk
iksftikllfnkngvlldnsnlgkaywnfrsgnsnvstayekaigfmpnlvaypkpsnsk
kyardivygtiylggkpdqpavikttfnqetgceysitfnfswsktyenvefettsftfs
yiaqe