PDB entry 4k57

View 4k57 on RCSB PDB site
Description: Structure of Thermus thermophilus 1-pyrroline-5-carboxylate dehydrogenase R100A mutant
Class: oxidoreductase
Keywords: aldehyde dehydrogenase, rossmann fold, nucleotide binding, oxidoreductase
Deposited on 2013-04-13, released 2013-06-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-08-28, with a file datestamp of 2013-08-23.
Experiment type: XRAY
Resolution: 1.54 Å
R-factor: 0.169
AEROSPACI score: 0.63 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Delta-1-pyrroline-5-carboxylate dehydrogenase
    Species: Thermus thermophilus [TaxId:262724]
    Gene: TT_C1213
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q72IB9 (2-517)
      • engineered mutation (101)
    Domains in SCOPe 2.08: d4k57a_
  • Chain 'B':
    Compound: Delta-1-pyrroline-5-carboxylate dehydrogenase
    Species: Thermus thermophilus [TaxId:262724]
    Gene: TT_C1213
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q72IB9 (2-517)
      • engineered mutation (101)
    Domains in SCOPe 2.08: d4k57b_
  • Heterogens: MRD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4k57A (A:)
ghmtvepfrnepietfqteearramrealrrvreefgrhyplyiggewvdtkermvslnp
sapsevvgttakagkaeaeaaleaawkafktwkdwpqedrsalllkaaalmrrrkrelea
tlvyevgknwveasadvaeaidfieyyaraalryrypavevvpypgednesfyvplgagv
viapwnfpvaiftgmimgpvavgntviakpaedavvvgakvfeifheagfppgvvnflpg
vgeevgaylvehprtrfinftgslevglkiyeaagrlapgqtwfkrayvetggkdaiivd
etadfdlaaegvvvsaygfqgqkcsaasrliltqgayepvlervlkraerlsvgpaeenp
dlgpvvsaeqerkvlsyieigknegqlvlggkrlegegyfiaptvftevppkariaqeei
fgpvlsvirvkdfaealevandtpygltggvysrkrehlewarrefhvgnlyfnrkitga
lvgvqpfggfklsgtnaktgaldylrlflemkavaerf

    Sequence, based on observed residues (ATOM records): (download) 
    >4k57A (A:)
mtvepfrnepietfqteearramrealrrvreefgrhyplyiggewvdtkermvslnpsa
psevvgttakagkaeaeaaleaawkafktwkdwpqedrsalllkaaalmrrrkreleatl
vyevgknwveasadvaeaidfieyyaraalryrypavevvpypgednesfyvplgagvvi
apwnfpvaiftgmimgpvavgntviakpaedavvvgakvfeifheagfppgvvnflpgvg
eevgaylvehprtrfinftgslevglkiyeaagrlapgqtwfkrayvetggkdaiivdet
adfdlaaegvvvsaygfqgqkcsaasrliltqgayepvlervlkraerlsvgpaeenpdl
gpvvsaeqerkvlsyieigknegqlvlggkrlegegyfiaptvftevppkariaqeeifg
pvlsvirvkdfaealevandtpygltggvysrkrehlewarrefhvgnlyfnrkitgalv
gvqpfggfklsgtnaktgaldylrlflemkavaerf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4k57B (B:)
ghmtvepfrnepietfqteearramrealrrvreefgrhyplyiggewvdtkermvslnp
sapsevvgttakagkaeaeaaleaawkafktwkdwpqedrsalllkaaalmrrrkrelea
tlvyevgknwveasadvaeaidfieyyaraalryrypavevvpypgednesfyvplgagv
viapwnfpvaiftgmimgpvavgntviakpaedavvvgakvfeifheagfppgvvnflpg
vgeevgaylvehprtrfinftgslevglkiyeaagrlapgqtwfkrayvetggkdaiivd
etadfdlaaegvvvsaygfqgqkcsaasrliltqgayepvlervlkraerlsvgpaeenp
dlgpvvsaeqerkvlsyieigknegqlvlggkrlegegyfiaptvftevppkariaqeei
fgpvlsvirvkdfaealevandtpygltggvysrkrehlewarrefhvgnlyfnrkitga
lvgvqpfggfklsgtnaktgaldylrlflemkavaerf

    Sequence, based on observed residues (ATOM records): (download) 
    >4k57B (B:)
mtvepfrnepietfqteearramrealrrvreefgrhyplyiggewvdtkermvslnpsa
psevvgttakagkaeaeaaleaawkafktwkdwpqedrsalllkaaalmrrrkreleatl
vyevgknwveasadvaeaidfieyyaraalryrypavevvpypgednesfyvplgagvvi
apwnfpvaiftgmimgpvavgntviakpaedavvvgakvfeifheagfppgvvnflpgvg
eevgaylvehprtrfinftgslevglkiyeaagrlapgqtwfkrayvetggkdaiivdet
adfdlaaegvvvsaygfqgqkcsaasrliltqgayepvlervlkraerlsvgpaeenpdl
gpvvsaeqerkvlsyieigknegqlvlggkrlegegyfiaptvftevppkariaqeeifg
pvlsvirvkdfaealevandtpygltggvysrkrehlewarrefhvgnlyfnrkitgalv
gvqpfggfklsgtnaktgaldylrlflemkavaerf