PDB entry 4jzf
View 4jzf on RCSB PDB site
Description: Structure of factor VIIA in complex with the inhibitor 2-{2-[(3-carbamoylphenyl)carbamoyl]-6-methoxypyridin-3-yl}-5-{[(2S)-1-hydroxy-3,3-dimethylbutan-2-yl]carbamoyl}benzoic acid
Class: hydrolase/hydrolase inhibitor
Keywords: glycoprotein, serine protease, plasma, blood coagulation factor, protein inhibitor complex, calcium binding, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on
2013-04-02, released
2013-08-21
The last revision prior to the SCOPe 2.03 freeze date was dated
2013-09-04, with a file datestamp of
2013-08-30.
Experiment type: XRAY
Resolution: 1.84 Å
R-factor: 0.181
AEROSPACI score: 0.51
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'H':
Compound: Factor VIIa (Heavy Chain)
Species: Homo sapiens [TaxId:9606]
Gene: F7
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d4jzfh_ - Chain 'L':
Compound: Factor VIIa (Light Chain)
Species: Homo sapiens [TaxId:9606]
Gene: F7
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d4jzfl_ - Heterogens: 1NL, CA, SO4, GOL, HOH
PDB Chain Sequences:
- Chain 'H':
Sequence; same for both SEQRES and ATOM records: (download)
>4jzfH (H:)
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
seprpgvllrapfp
- Chain 'L':
Sequence; same for both SEQRES and ATOM records: (download)
>4jzfL (L:)
icvnenggceqycsdhtgtkrscrchegyslladgvsctptveypcgkipilekr