PDB entry 4jv4

View 4jv4 on RCSB PDB site
Description: Crystal Structure of RIalpha(91-379) bound to HE33, a N6 di-propyl substituted cAMP analog
Class: transferase/transferase inhibitor
Keywords: cAMP-dependent protein kinase, cyclic nucleotide analogs, isoform selectivity, fluorescence anisotropy, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2013-03-25, released 2013-09-18
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-10-30, with a file datestamp of 2013-10-25.
Experiment type: XRAY
Resolution: 2.95 Å
R-factor: 0.222
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cAMP-dependent protein kinase type I-alpha regulatory subunit
    Species: Bos taurus [TaxId:9913]
    Gene: PRKAR1A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4jv4a1, d4jv4a2
  • Heterogens: 1OR

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4jv4A (A:)
rrrrgaisaevyteedaasyvrkvipkdyktmaalakaieknvlfshlddnersdifdam
fpvsfiagetviqqgdegdnfyvidqgemdvyvnnewatsvgeggsfgelaliygtpraa
tvkaktnvklwgidrdsyrrilmgstlrkrkmyeeflskvsilesldkwerltvadalep
vqfedgqkivvqgepgdeffiilegsaavlqrrseneefvevgrlgpsdyfgeiallmnr
praatvvargplkcvkldrprfervlgpcsdilkrniqqynsfvslsv

    Sequence, based on observed residues (ATOM records): (download) 
    >4jv4A (A:)
daasyvrkvipkdyktmaalakaieknvlfshlddnersdifdamfpvsfiagetviqqg
degdnfyvidqgemdvyvnnewatsvgeggsfgelaliygtpraatvkaktnvklwgidr
dsyrrilmgstlrkrkmyeeflskvsilesldkwerltvadalepvqfedgqkivvqgep
gdeffiilegsaavlqrfvevgrlgpsdyfgeiallmnrpraatvvargplkcvkldrpr
fervlgpcsdilkrniqqyns