PDB entry 4jug

View 4jug on RCSB PDB site
Description: Crystal structure of 1918 pandemic influenza virus hemagglutinin mutant D225G
Class: viral protein
Keywords: virus attachment, membrane fusion, VIRAL PROTEIN
Deposited on 2013-03-24, released 2013-05-01
The last revision prior to the SCOPe 2.05 freeze date was dated 2013-08-07, with a file datestamp of 2013-08-02.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.21
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hemagglutinin
    Species: Influenza A virus [TaxId:59375]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9WFX3 (0-321)
      • engineered mutation (221)
      • expression tag (322-323)
    Domains in SCOPe 2.05: d4juga_
  • Chain 'B':
    Compound: Hemagglutinin
    Species: Influenza A virus [TaxId:59375]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4jugb_
  • Chain 'C':
    Compound: Hemagglutinin
    Species: Influenza A virus [TaxId:59375]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9WFX3 (0-321)
      • engineered mutation (221)
      • expression tag (322-323)
    Domains in SCOPe 2.05: d4jugc_
  • Chain 'D':
    Compound: Hemagglutinin
    Species: Influenza A virus [TaxId:59375]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4jugd_
  • Chain 'E':
    Compound: Hemagglutinin
    Species: Influenza A virus [TaxId:59375]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9WFX3 (0-321)
      • engineered mutation (221)
      • expression tag (322-323)
    Domains in SCOPe 2.05: d4juge_
  • Chain 'F':
    Compound: Hemagglutinin
    Species: Influenza A virus [TaxId:59375]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4jugf_
  • Chain 'G':
    Compound: Hemagglutinin
    Species: Influenza A virus [TaxId:59375]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9WFX3 (0-321)
      • engineered mutation (221)
      • expression tag (322-323)
    Domains in SCOPe 2.05: d4jugg_
  • Chain 'H':
    Compound: Hemagglutinin
    Species: Influenza A virus [TaxId:59375]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4jugh_
  • Chain 'I':
    Compound: Hemagglutinin
    Species: Influenza A virus [TaxId:59375]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9WFX3 (0-321)
      • engineered mutation (221)
      • expression tag (322-323)
    Domains in SCOPe 2.05: d4jugi_
  • Chain 'J':
    Compound: Hemagglutinin
    Species: Influenza A virus [TaxId:59375]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4jugj_
  • Chain 'K':
    Compound: Hemagglutinin
    Species: Influenza A virus [TaxId:59375]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9WFX3 (0-321)
      • engineered mutation (221)
      • expression tag (322-323)
    Domains in SCOPe 2.05: d4jugk_
  • Chain 'L':
    Compound: Hemagglutinin
    Species: Influenza A virus [TaxId:59375]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4jugl_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4jugA (A:)
dticigyhannstdtvdtvleknvtvthsvnlledshngklcklkgiaplqlgkcniagw
llgnpecdllltasswsyivetsnsengtcypgdfidyeelreqlssvssfekfeifpkt
sswpnhettkgvtaacsyagassfyrnllwltkkgssypklsksyvnnkgkevlvlwgvh
hpptgtdqqslyqnadayvsvgsskynrrftpeiaarpkvrgqagrmnyywtllepgdti
tfeatgnliapwyafalnrgsgsgiitsdapvhdcntkcqtphgainsslpfqnihpvti
gecpkyvrstklrmatglrnipar

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4jugB (B:)
glfgaiagfieggwtgmidgwygyhhqneqgsgyaadqkstqnaidgitnkvnsviekmn
tqftavgkefnnlerrienlnkkvddgfldiwtynaellvllenertldfhdsnvrnlye
kvksqlknnakeigngcfefyhkcddacmesvrngtydypkyseesklnr

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4jugC (C:)
dticigyhannstdtvdtvleknvtvthsvnlledshngklcklkgiaplqlgkcniagw
llgnpecdllltasswsyivetsnsengtcypgdfidyeelreqlssvssfekfeifpkt
sswpnhettkgvtaacsyagassfyrnllwltkkgssypklsksyvnnkgkevlvlwgvh
hpptgtdqqslyqnadayvsvgsskynrrftpeiaarpkvrgqagrmnyywtllepgdti
tfeatgnliapwyafalnrgsgsgiitsdapvhdcntkcqtphgainsslpfqnihpvti
gecpkyvrstklrmatglrnipar

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4jugD (D:)
glfgaiagfieggwtgmidgwygyhhqneqgsgyaadqkstqnaidgitnkvnsviekmn
tqftavgkefnnlerrienlnkkvddgfldiwtynaellvllenertldfhdsnvrnlye
kvksqlknnakeigngcfefyhkcddacmesvrngtydypkyseesklnr

    Sequence, based on observed residues (ATOM records): (download) 
    >4jugD (D:)
glfgaiagfieggwtgmidgwygyhhqneqgsgyaadqkstqnaidgitnkvnsviekmn
tqftavgkefnnlerrienlnkkvddgfldiwtynaellvllenertldfhdsnvrnlye
kvksqlknnakeigngcfefyhkcddacmesvrngtydypkyseeskln

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4jugE (E:)
dticigyhannstdtvdtvleknvtvthsvnlledshngklcklkgiaplqlgkcniagw
llgnpecdllltasswsyivetsnsengtcypgdfidyeelreqlssvssfekfeifpkt
sswpnhettkgvtaacsyagassfyrnllwltkkgssypklsksyvnnkgkevlvlwgvh
hpptgtdqqslyqnadayvsvgsskynrrftpeiaarpkvrgqagrmnyywtllepgdti
tfeatgnliapwyafalnrgsgsgiitsdapvhdcntkcqtphgainsslpfqnihpvti
gecpkyvrstklrmatglrnipar

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >4jugF (F:)
glfgaiagfieggwtgmidgwygyhhqneqgsgyaadqkstqnaidgitnkvnsviekmn
tqftavgkefnnlerrienlnkkvddgfldiwtynaellvllenertldfhdsnvrnlye
kvksqlknnakeigngcfefyhkcddacmesvrngtydypkyseesklnr

    Sequence, based on observed residues (ATOM records): (download) 
    >4jugF (F:)
glfgaiagfieggwtgmidgwygyhhqneqgsgyaadqkstqnaidgitnkvnsviekmn
tqftavgkefnnlerrienlnkkvddgfldiwtynaellvllenertldfhdsnvrnlye
kvksqlknnakeigngcfefyhkcddacmesvrngtydypkysee

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4jugG (G:)
dticigyhannstdtvdtvleknvtvthsvnlledshngklcklkgiaplqlgkcniagw
llgnpecdllltasswsyivetsnsengtcypgdfidyeelreqlssvssfekfeifpkt
sswpnhettkgvtaacsyagassfyrnllwltkkgssypklsksyvnnkgkevlvlwgvh
hpptgtdqqslyqnadayvsvgsskynrrftpeiaarpkvrgqagrmnyywtllepgdti
tfeatgnliapwyafalnrgsgsgiitsdapvhdcntkcqtphgainsslpfqnihpvti
gecpkyvrstklrmatglrnipar

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4jugH (H:)
glfgaiagfieggwtgmidgwygyhhqneqgsgyaadqkstqnaidgitnkvnsviekmn
tqftavgkefnnlerrienlnkkvddgfldiwtynaellvllenertldfhdsnvrnlye
kvksqlknnakeigngcfefyhkcddacmesvrngtydypkyseesklnr

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4jugI (I:)
dticigyhannstdtvdtvleknvtvthsvnlledshngklcklkgiaplqlgkcniagw
llgnpecdllltasswsyivetsnsengtcypgdfidyeelreqlssvssfekfeifpkt
sswpnhettkgvtaacsyagassfyrnllwltkkgssypklsksyvnnkgkevlvlwgvh
hpptgtdqqslyqnadayvsvgsskynrrftpeiaarpkvrgqagrmnyywtllepgdti
tfeatgnliapwyafalnrgsgsgiitsdapvhdcntkcqtphgainsslpfqnihpvti
gecpkyvrstklrmatglrnipar

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >4jugJ (J:)
glfgaiagfieggwtgmidgwygyhhqneqgsgyaadqkstqnaidgitnkvnsviekmn
tqftavgkefnnlerrienlnkkvddgfldiwtynaellvllenertldfhdsnvrnlye
kvksqlknnakeigngcfefyhkcddacmesvrngtydypkyseesklnr

    Sequence, based on observed residues (ATOM records): (download) 
    >4jugJ (J:)
glfgaiagfieggwtgmidgwygyhhqneqgsgyaadqkstqnaidgitnkvnsviekmn
tqftavgkefnnlerrienlnkkvddgfldiwtynaellvllenertldfhdsnvrnlye
kvksqlknnakeigngcfefyhkcddacmesvrngtydypkyseesk

  • Chain 'K':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4jugK (K:)
dticigyhannstdtvdtvleknvtvthsvnlledshngklcklkgiaplqlgkcniagw
llgnpecdllltasswsyivetsnsengtcypgdfidyeelreqlssvssfekfeifpkt
sswpnhettkgvtaacsyagassfyrnllwltkkgssypklsksyvnnkgkevlvlwgvh
hpptgtdqqslyqnadayvsvgsskynrrftpeiaarpkvrgqagrmnyywtllepgdti
tfeatgnliapwyafalnrgsgsgiitsdapvhdcntkcqtphgainsslpfqnihpvti
gecpkyvrstklrmatglrnipar

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >4jugL (L:)
glfgaiagfieggwtgmidgwygyhhqneqgsgyaadqkstqnaidgitnkvnsviekmn
tqftavgkefnnlerrienlnkkvddgfldiwtynaellvllenertldfhdsnvrnlye
kvksqlknnakeigngcfefyhkcddacmesvrngtydypkyseesklnr

    Sequence, based on observed residues (ATOM records): (download) 
    >4jugL (L:)
glfgaiagfieggwtgmidgwygyhhqneqgsgyaadqkstqnaidgitnkvnsviekmn
tqftavgkefnnlerrienlnkkvddgfldiwtynaellvllenertldfhdsnvrnlye
kvksqlknnakeigngcfefyhkcddacmesvrngtydypkysee