PDB entry 4jq1

View 4jq1 on RCSB PDB site
Description: AKR1C2 complex with naproxen
Class: Oxidoreductase/Oxidoreductase inhibitor
Keywords: OXIDOREDUCTASE, Oxidoreductase-Oxidoreductase inhibitor complex
Deposited on 2013-03-19, released 2014-04-02
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-10-15, with a file datestamp of 2014-10-10.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.194
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Aldo-keto reductase family 1 member C2
    Species: Homo sapiens [TaxId:9606]
    Gene: AKR1C2, DDH2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4jq1a_
  • Chain 'B':
    Compound: Aldo-keto reductase family 1 member C2
    Species: Homo sapiens [TaxId:9606]
    Gene: AKR1C2, DDH2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4jq1b_
  • Heterogens: NPS, NAP, EDO, TLA, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4jq1A (A:)
mdskyqcvklndghfmpvlgfgtyapaevpkskaleavklaieagfhhidsahvynneeq
vglairskiadgsvkredifytsklwsnshrpelvrpalerslknlqldyvdlylihfpv
svkpgeevipkdengkilfdtvdlcatweamekckdaglaksigvsnfnhrllemilnkp
glkykpvcnqvechpyfnqrklldfckskdivlvaysalgshreepwvdpnspvlledpv
lcalakkhkrtpalialryqlqrgvvvlaksyneqrirqnvqvfefqltseemkaidgln
rnvryltldifagppnypfsdeylehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4jq1A (A:)
kyqcvklndghfmpvlgfgtyapaevpkskaleavklaieagfhhidsahvynneeqvgl
airskiadgsvkredifytsklwsnshrpelvrpalerslknlqldyvdlylihfpvsvk
pgeevipkdengkilfdtvdlcatweamekckdaglaksigvsnfnhrllemilnkpglk
ykpvcnqvechpyfnqrklldfckskdivlvaysalgshreepwvdpnspvlledpvlca
lakkhkrtpalialryqlqrgvvvlaksyneqrirqnvqvfefqltseemkaidglnrnv
ryltldifagppnypf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4jq1B (B:)
mdskyqcvklndghfmpvlgfgtyapaevpkskaleavklaieagfhhidsahvynneeq
vglairskiadgsvkredifytsklwsnshrpelvrpalerslknlqldyvdlylihfpv
svkpgeevipkdengkilfdtvdlcatweamekckdaglaksigvsnfnhrllemilnkp
glkykpvcnqvechpyfnqrklldfckskdivlvaysalgshreepwvdpnspvlledpv
lcalakkhkrtpalialryqlqrgvvvlaksyneqrirqnvqvfefqltseemkaidgln
rnvryltldifagppnypfsdeylehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4jq1B (B:)
kyqcvklndghfmpvlgfgtyapaevpkskaleavklaieagfhhidsahvynneeqvgl
airskiadgsvkredifytsklwsnshrpelvrpalerslknlqldyvdlylihfpvsvk
pgeevipkdengkilfdtvdlcatweamekckdaglaksigvsnfnhrllemilnkpglk
ykpvcnqvechpyfnqrklldfckskdivlvaysalgshreepwvdpnspvlledpvlca
lakkhkrtpalialryqlqrgvvvlaksyneqrirqnvqvfefqltseemkaidglnrnv
ryltldifagppnypf