PDB entry 4jpw
View 4jpw on RCSB PDB site
Description: Crystal structure of broadly and potently neutralizing antibody 12a21 in complex with hiv-1 strain 93th057 gp120 mutant
Class: viral protein/immune system
Keywords: hiv, gp120, cd4-binding site, 12a21, neutralization, vaccine, antibody, envelope protein, viral protein-immune system complex
Deposited on
2013-03-19, released
2013-04-17
The last revision prior to the SCOPe 2.07 freeze date was dated
2013-08-21, with a file datestamp of
2013-08-16.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.209
AEROSPACI score: 0.28
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'G':
Compound: hiv-1 clade a/e strain 73th057 gp120 with mutation h375s
Species: Human immunodeficiency virus 1 [TaxId:11676]
Database cross-references and differences (RAF-indexed):
- Chain 'H':
Compound: heavy chain of antibody 12a21
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Chain 'L':
Compound: light chain of antibody 12a21
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d4jpwl1, d4jpwl2 - Heterogens: NAG, EPE, HOH
PDB Chain Sequences:
- Chain 'G':
No sequence available.
- Chain 'H':
No sequence available.
- Chain 'L':
Sequence, based on SEQRES records: (download)
>4jpwL (L:)
diqmtqspsslsasvgdrvtincqagqgigsslnwyqkkpgrapkllvhgasnlqrgvps
rfsgsgfhttftltisslqpddvatyfcavfqwfgpgtkvdikrtvaapsvfifppsdeq
lksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstltlska
dyekhkvyacevthqglrspvtksfnrgec
Sequence, based on observed residues (ATOM records): (download)
>4jpwL (L:)
diqmtqspsslsasvgdrvtincqagqgigsslnwyqkkpgrapkllvhgasnlqrgvps
rfsgsgfhttftltisslqpddvatyfcavfqwfgpgtkvdikrtvaapsvfifppsdeq
lksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstltlska
dyekhkvyacevthqglrspvtksfnrg