PDB entry 4jlx

View 4jlx on RCSB PDB site
Description: Structure of porcine cyclic GMP-AMP synthase (cGAS)
Class: DNA binding protein
Keywords: DNA binding protein
Deposited on 2013-03-13, released 2013-06-12
The last revision prior to the SCOPe 2.05 freeze date was dated 2013-07-10, with a file datestamp of 2013-07-05.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.189
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Uncharacterized protein
    Species: Sus scrofa [TaxId:9823]
    Gene: Mb21d1
    Database cross-references and differences (RAF-indexed):
    • Uniprot I3LM39 (3-365)
      • see remark 999 (137)
    Domains in SCOPe 2.05: d4jlxa1, d4jlxa2
  • Heterogens: ZN, MLI, GOL, PG4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4jlxA (A:)
    gamgawklqtvlekvrlsrheiseaaevvnwvvehllrrlqggesefkgvallrtgsyye
    rvkisapnefdvmfklevpriqleeycnsgahyfvkfkrnpggnpleqflekeilsaskm
    lskfrkiikeeikniedtgvtverkrrgspavtlliskpkeisvdiilalesksswpast
    qkglpisqwlgakvknnlkrqpfylvpkhakegsgfqeetwrlsfshiekdilknhgqsk
    tcceidgvkccrkeclklmkylleqlkkkfgnrrelakfcsyhvktaffhvctqdphdnq
    whlknleccfdncvayflqclkteqlanyfipgvnlfsrdlidkpskeflskqieyernn
    gfpvfw
    

    Sequence, based on observed residues (ATOM records): (download)
    >4jlxA (A:)
    gawklqtvlekvrlsrheiseaaevvnwvvehllrrlqggesefkgvallrtgsapnefd
    vmfklevpriqleeycnsgahyfvkfkrnpggnpleqflekeilsaskmlskfrkiikee
    ikntgvtverkrgspavtlliskpkeisvdiilalesksswpastqkglpisqwlgakvk
    nnlkrqpfylvpkhakegsgfqeetwrlsfshiekdilknhgqsktcceidgvkccrkec
    lklmkylleqlkkkfgnrrelakfcsyhvktaffhvctqdphdnqwhlknleccfdncva
    yflqclkteqlanyfipgvnlfsrdlidkpskeflskqieyernngfpvfw