PDB entry 4jih

View 4jih on RCSB PDB site
Description: Crystal Structure Of AKR1B10 Complexed With NADP+ And Epalrestat
Class: oxidoreductase/oxidoreductase inhibitor
Keywords: TIM barrel, oxidoreductases, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex
Deposited on 2013-03-06, released 2013-10-23
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-11-27, with a file datestamp of 2013-11-22.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.153
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Aldo-keto reductase family 1 member B10
    Species: Homo sapiens [TaxId:9606]
    Gene: AKR1B10, AKR1B11
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60218 (2-317)
      • expression tag (0-1)
      • conflict (314)
    Domains in SCOPe 2.07: d4jiha1, d4jiha2
  • Heterogens: EPR, NAP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4jihA (A:)
shmatfvelstkakmpivglgtwksplgkvkeavkvaidagyrhidcayvyqnehevgea
iqekiqekavkredlfivsklwptfferplvrkafektlkdlklsyldvylihwpqgfks
gddlfpkddkgnaiggkatfldaweameelvdeglvkalgvsnfshfqiekllnkpglky
kpvtnqvechpyltqekliqychskgitvtaysplgspdrpwakpedpslledpkikeia
akhkktaaqvlirfhiqrnvivipksvtpariveniqvfdfklsdeematilsfnrnwra
cnvlqsshledypfdaey