PDB entry 4j4n

View 4j4n on RCSB PDB site
Description: Crystal structure of FK506 binding domain of plasmodium falciparum FKBP35 in complex with D44
Class: isomerase/isomerase inhibitor
Keywords: D44, FKBP35, FK506 BINDING, ISOMERASE-ISOMERASE INHIBITOR complex
Deposited on 2013-02-07, released 2013-09-11
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-09-11, with a file datestamp of 2013-09-06.
Experiment type: XRAY
Resolution: 2.75 Å
R-factor: 0.229
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: FK506-binding protein (FKBP)-type peptidyl-propyl isomerase
    Species: PLASMODIUM FALCIPARUM [TaxId:36329]
    Gene: FKBP35, PFL2275C
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8I4V8 (Start-126)
      • expression tag (127-128)
    Domains in SCOPe 2.07: d4j4na1, d4j4na2
  • Chain 'B':
    Compound: FK506-binding protein (FKBP)-type peptidyl-propyl isomerase
    Species: PLASMODIUM FALCIPARUM [TaxId:36329]
    Gene: FKBP35, PFL2275C
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8I4V8 (Start-126)
      • expression tag (127)
    Domains in SCOPe 2.07: d4j4nb1, d4j4nb2
  • Chain 'C':
    Compound: FK506-binding protein (FKBP)-type peptidyl-propyl isomerase
    Species: PLASMODIUM FALCIPARUM [TaxId:36329]
    Gene: FKBP35, PFL2275C
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4j4nc_
  • Heterogens: D44, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4j4nA (A:)
mtteqefekveltadggviktilkkgdegeenipkkgnevtvhyvgklestgkvfdssfd
rnvpfkfhleqgevikgwdicvssmrknekclvriesmygygdegcgesipgnsvllfei
ellsfrele

    Sequence, based on observed residues (ATOM records): (download) 
    >4j4nA (A:)
fekveltadggviktilkkgdegeenipkkgnevtvhyvgklestgkvfdssfdrnvpfk
fhleqgevikgwdicvssmrknekclvriesmygygdegcgesipgnsvllfeiellsfr
ele

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4j4nB (B:)
mtteqefekveltadggviktilkkgdegeenipkkgnevtvhyvgklestgkvfdssfd
rnvpfkfhleqgevikgwdicvssmrknekclvriesmygygdegcgesipgnsvllfei
ellsfrele

    Sequence, based on observed residues (ATOM records): (download) 
    >4j4nB (B:)
fekveltadggviktilkkgdegeenipkkgnevtvhyvgklestgkvfdssfdrnvpfk
fhleqgevikgwdicvssmrknekclvriesmygygdegcgesipgnsvllfeiellsfr
el

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4j4nC (C:)
mtteqefekveltadggviktilkkgdegeenipkkgnevtvhyvgklestgkvfdssfd
rnvpfkfhleqgevikgwdicvssmrknekclvriesmygygdegcgesipgnsvllfei
ellsfrele

    Sequence, based on observed residues (ATOM records): (download) 
    >4j4nC (C:)
fekveltadggviktilkkgdegeenipkkgnevtvhyvgklestgkvfdssfdrnvpfk
fhleqgevikgwdicvssmrknekclvriesmygygdegcgesipgnsvllfeiellsfr
e