PDB entry 4j03

View 4j03 on RCSB PDB site
Description: Crystal structure of human soluble epoxide hydrolase complexed with fulvestrant
Class: Hydrolase/Hydrolase inhibitor
Keywords: DOMAIN-SWAPPED DIMER, Hydrolase-Hydrolase inhibitor complex
Deposited on 2013-01-30, released 2013-06-05
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-06-26, with a file datestamp of 2013-06-21.
Experiment type: XRAY
Resolution: 2.92 Å
R-factor: 0.191
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bifunctional epoxide hydrolase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: EPHX2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4j03a1, d4j03a2
  • Heterogens: PO4, MG, FVS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4j03A (A:)
mtlraavfdldgvlalpavfgvlgrteealalprgllndafqkggpegattrlmkgeitl
sqwiplmeencrkcsetakvclpknfsikeifdkaisarkinrpmlqaalmlrkkgftta
iltntwlddraerdglaqlmcelkmhfdfliescqvgmvkpepqiykflldtlkaspsev
vflddiganlkpardlgmvtilvqdtdtalkelekvtgiqllntpaplptscnpsdmshg
yvtvkprvrlhfvelgsgpavclchgfpeswyswryqipalaqagyrvlamdmkgygess
appeieeycmevlckemvtfldklglsqavfighdwggmlvwymalfypervravaslnt
pfipanpnmsplesikanpvfdyqlyfqepgvaeaeleqnlsrtfkslfrasdesvlsmh
kvceagglfvnspeepslsrmvteeeiqfyvqqfkksgfrgplnwyrnmernwkwacksl
grkilipalmvtaekdfvlvpqmsqhmedwiphlkrghiedcghwtqmdkptevnqilik
wldsdarnppvvskm

    Sequence, based on observed residues (ATOM records): (download) 
    >4j03A (A:)
mtlraavfdldgvlalpavfgvlgrteealalprgllndafqkggpegattrlmkgeitl
sqwiplmeencrkcsetakvclpknfsikeifdkaisarkinrpmlqaalmlrkkgftta
iltntwlddraerdglaqlmcelkmhfdfliescqvgmvkpepqiykflldtlkaspsev
vflddiganlkpardlgmvtilvqdtdtalkelekvtgiqllntpaplptscnpsdmshg
yvtvkprvrlhfvelgsgpavclchgfpeswyswryqipalaqagyrvlamdmkgygess
appeieeycmevlckemvtfldklglsqavfighdwggmlvwymalfypervravaslnt
pfipanpnmsplesikanpvfdyqlyfqepgvaeaeleqnlsrtfkslfrasdesvlsmh
kvceagglfvnspeepslsrmvteeeiqfyvqqfkksgfrgplnwyrnmernwkwacksl
grkilipalmvtaekdfvlvpqmsqhmedwiphlkrghiedcghwtqmdkptevnqilik
wldsdarn