PDB entry 4izd

View 4izd on RCSB PDB site
Description: Crystal structure of DmdD E121A in complex with MMPA-CoA
Class: hydrolase/substrate
Keywords: ENOYL-COA HYDRATASE, HYDROLASE, Dimethyl-sulphoniopropionate (DMSP) METABOLISM, methylthioacryloyl-CoA (MTA-CoA), CROTONASE FOLD, hydrolase-substrate complex
Deposited on 2013-01-29, released 2013-06-05
The last revision prior to the SCOPe 2.04 freeze date was dated 2013-06-05, with a file datestamp of 2013-05-31.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.16
AEROSPACI score: 0.55 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Enoyl-CoA hydratase/isomerase family protein
    Species: Ruegeria pomeroyi [TaxId:246200]
    Gene: dmdD
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5LLW6
      • engineered mutation (120)
    Domains in SCOPe 2.04: d4izda_
  • Chain 'B':
    Compound: Enoyl-CoA hydratase/isomerase family protein
    Species: Ruegeria pomeroyi [TaxId:246200]
    Gene: dmdD
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5LLW6
      • engineered mutation (120)
    Domains in SCOPe 2.04: d4izdb_
  • Heterogens: 1HE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4izdA (A:)
mtqdvtsgysnldldlrdngvcvvtlnrpdkrnaldvatieelvtffstahrkgvravvl
tgagdhfcagldlvehwkadrsaddfmhvclrwheafnkmeyggvpiiaalrgavvgggl
alasaahlrvmdqstyfalpegqrgiftgggatirvsdmigkyrmidmiltgrvyqgqea
adlglaqyitegssfdkameladkiasnlpltnfaicsaishmqnmsgldaayaeafvgg
ivntqpaarerleafanktaarvrpnslehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4izdA (A:)
tqdvtsgysnldldlrdngvcvvtlnrpdkrnaldvatieelvtffstahrkgvravvlt
gagdhfcagldlvehwkadrsaddfmhvclrwheafnkmeyggvpiiaalrgavvgggla
lasaahlrvmdqstyfalpegqrgiftgggatirvsdmigkyrmidmiltgrvyqgqeaa
dlglaqyitegssfdkameladkiasnlpltnfaicsaishmqnmsgldaayaeafvggi
vntqpaarerlea

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4izdB (B:)
mtqdvtsgysnldldlrdngvcvvtlnrpdkrnaldvatieelvtffstahrkgvravvl
tgagdhfcagldlvehwkadrsaddfmhvclrwheafnkmeyggvpiiaalrgavvgggl
alasaahlrvmdqstyfalpegqrgiftgggatirvsdmigkyrmidmiltgrvyqgqea
adlglaqyitegssfdkameladkiasnlpltnfaicsaishmqnmsgldaayaeafvgg
ivntqpaarerleafanktaarvrpnslehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4izdB (B:)
tqdvtsgysnldldlrdngvcvvtlnrpdkrnaldvatieelvtffstahrkgvravvlt
gagdhfcagldlvehwkadrsaddfmhvclrwheafnkmeyggvpiiaalrgavvgggla
lasaahlrvmdqstyfalpegqrgiftgggatirvsdmigkyrmidmiltgrvyqgqeaa
dlglaqyitegssfdkameladkiasnlpltnfaicsaishmqnmsgldaayaeafvggi
vntqpaarerleafankta