PDB entry 4ivr

View 4ivr on RCSB PDB site
Description: Crystal structure of thymidine kinase from herpes simplex virus type 1 in complex with IN52/10
Class: transferase
Keywords: DNA synthesis, PET imaging TRACER, ATP binding, nucleotide binding, TRANSFERASE
Deposited on 2013-01-23, released 2013-02-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidine kinase
    Species: Human herpesvirus 1 [TaxId:10299]
    Gene: TK, TK (UL23), UL23
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4ivra_
  • Chain 'B':
    Compound: Thymidine kinase
    Species: Human herpesvirus 1 [TaxId:10299]
    Gene: TK, TK (UL23), UL23
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4ivrb_
  • Heterogens: N50, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4ivrA (A:)
mptllrvyidgphgmgkttttqllvalgsrddivyvpepmtywrvlgasetianiyttqh
rldqgeisagdaavvmtsaqitmgmpyavtdavlaphiggeagsshapppaltlifdrhp
iaallcypaarylmgsmtpqavlafvalipptlpgtnivlgalpedrhidrlakrqrpge
rldlamlaairrvygllantvrylqcggswredwgqlsgtavppqgaepqsnagprphig
dtlftlfrapellapngdlynvfawaldvlakrlrsmhvfildydqspagcrdallqlts
gmvqthvttpgsipticdlartfaremgean

    Sequence, based on observed residues (ATOM records): (download) 
    >4ivrA (A:)
mptllrvyidgphgmgkttttqllvalgsrddivyvpepmtywrvlgasetianiyttqh
rldqgeisagdaavvmtsaqitmgmpyavtdavlaphiggeapppaltlifdrhpiaall
cypaarylmgsmtpqavlafvalipptlpgtnivlgalpedrhidrlakpgerldlamla
airrvygllantvrylqcggswredwgqlsgnagprphigdtlftlfrapellapngdly
nvfawaldvlakrlrsmhvfildydqspagcrdallqltsgmvqthvttpgsipticdla
rtfaremge

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4ivrB (B:)
mptllrvyidgphgmgkttttqllvalgsrddivyvpepmtywrvlgasetianiyttqh
rldqgeisagdaavvmtsaqitmgmpyavtdavlaphiggeagsshapppaltlifdrhp
iaallcypaarylmgsmtpqavlafvalipptlpgtnivlgalpedrhidrlakrqrpge
rldlamlaairrvygllantvrylqcggswredwgqlsgtavppqgaepqsnagprphig
dtlftlfrapellapngdlynvfawaldvlakrlrsmhvfildydqspagcrdallqlts
gmvqthvttpgsipticdlartfaremgean

    Sequence, based on observed residues (ATOM records): (download) 
    >4ivrB (B:)
mptllrvyidgphgmgkttttqllvalgsrddivyvpepmtywrvlgasetianiyttqh
rldqgeisagdaavvmtsaqitmgmpyavtdavlaphiggeapppaltlifdrhpiaall
cypaarylmgsmtpqavlafvalipptlpgtnivlgalpedrhidrlakrqrpgerldla
mlaairrvygllantvrylqcggswredwgqlprphigdtlftlfrapellapngdlynv
fawaldvlakrlrsmhvfildydqspagcrdallqltsgmvqthvttpgsipticdlart
faremge