PDB entry 4isw

View 4isw on RCSB PDB site
Description: Crystal Structure of Phosphorylated C.elegans Thymidylate Synthase in Complex with dUMP
Class: transferase
Keywords: PHOSPHOPROTEIN, PROTEIN HOMODIMER, DEOXYNUCLEOTIDE BIOSYNTHESIS, Phosphorylation, TRANSFERASE
Deposited on 2013-01-17, released 2013-12-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-01-15, with a file datestamp of 2014-01-10.
Experiment type: XRAY
Resolution: 3.14 Å
R-factor: 0.236
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidylate synthase
    Species: Caenorhabditis elegans [TaxId:6239]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4iswa_
  • Chain 'B':
    Compound: Thymidylate synthase
    Species: Caenorhabditis elegans [TaxId:6239]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4iswb_
  • Heterogens: UMP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4iswA (A:)
mevmnkeniiadapsdvvktvqqqvhlnqdeykylkqveqilregtrrddrtgtgtisif
gmqskyclrngtipllttkrvywkgvleellwfisgstdgkllmeknvkiwekngdrafl
dnlgftsreegdlgpvygfqwrhfgakyvdchtdysgqgvdqlaevirqikeqpdsrrii
msawnpsdlgqmvlppchtmcqfyvdngelscqlyqrsgdmglgvpfnlasygllthmia
kvcglkpgtlvhtlgdahvysnhvdalkiqldrepyafpkirftrdvasiddftsdmial
ddykchpkipmdmav

    Sequence, based on observed residues (ATOM records): (download) 
    >4iswA (A:)
qqvhlnqdeykylkqveqilregtrrddrtgtgtisifgmqskyclrngtipllttkrvy
wkgvleellwfisgstdgkllmeknvkiwekngdrafldnlgftsreegdlgpvygfqwr
hfgakyvdchtdysgqgvdqlaevirqikeqpdsrriimsawnpsdlgqmvlppchtmcq
fyvdngelscqlyqrsgdmglgvpfnlasygllthmiakvcglkpgtlvhtlgdahvysn
hvdalkiqldrepyafpkirftrdvasiddftsdmialddykchpkipmd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4iswB (B:)
mevmnkeniiadapsdvvktvqqqvhlnqdeykylkqveqilregtrrddrtgtgtisif
gmqskyclrngtipllttkrvywkgvleellwfisgstdgkllmeknvkiwekngdrafl
dnlgftsreegdlgpvygfqwrhfgakyvdchtdysgqgvdqlaevirqikeqpdsrrii
msawnpsdlgqmvlppchtmcqfyvdngelscqlyqrsgdmglgvpfnlasygllthmia
kvcglkpgtlvhtlgdahvysnhvdalkiqldrepyafpkirftrdvasiddftsdmial
ddykchpkipmdmav

    Sequence, based on observed residues (ATOM records): (download) 
    >4iswB (B:)
qqvhlnqdeykylkqveqilregtrrddrtgtgtisifgmqskyclrngtipllttkrvy
wkgvleellwfisgstdgkllmeknvkiwekngdrafldnlgftsreegdlgpvygfqwr
hfgakyvdchtdysgqgvdqlaevirqikeqpdsrriimsawnpsdlgqmvlppchtmcq
fyvdngelscqlyqrsgdmglgvpfnlasygllthmiakvcglkpgtlvhtlgdahvysn
hvdalkiqldrepyafpkirftrdvasiddftsdmialddykchpkipmd