PDB entry 4irr

View 4irr on RCSB PDB site
Description: Crystal Structure of C.elegans Thymidylate Synthase in Complex with dUMP
Class: transferase
Keywords: protein dimer, deoxynucleotide biosynthesis, transferase
Deposited on 2013-01-15, released 2014-01-29
The last revision prior to the SCOPe 2.06 freeze date was dated 2014-01-29, with a file datestamp of 2014-01-24.
Experiment type: XRAY
Resolution: 2.48 Å
R-factor: 0.233
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidylate synthase
    Species: Caenorhabditis elegans [TaxId:6239]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4irra_
  • Chain 'B':
    Compound: Thymidylate synthase
    Species: Caenorhabditis elegans [TaxId:6239]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4irrb_
  • Heterogens: UMP, DTT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4irrA (A:)
mevmnkeniiadapsdvvktvqqqvhlnqdeykylkqveqilregtrrddrtgtgtisif
gmqskyclrngtipllttkrvywkgvleellwfisgstdgkllmeknvkiwekngdrafl
dnlgftsreegdlgpvygfqwrhfgakyvdchtdysgqgvdqlaevirqikeqpdsrrii
msawnpsdlgqmvlppchtmcqfyvdngelscqlyqrsgdmglgvpfnlasygllthmia
kvcglkpgtlvhtlgdahvysnhvdalkiqldrepyafpkirftrdvasiddftsdmial
ddykchpkipmdmav

    Sequence, based on observed residues (ATOM records): (download) 
    >4irrA (A:)
qqvhlnqdeykylkqveqilregtrrddrtgtgtisifgmqskyclrngtipllttkrvy
wkgvleellwfisgstdgkllmeknvkiwekngdrafldnlgftsreegdlgpvygfqwr
hfgakyvdchtdysgqgvdqlaevirqikeqpdsrriimsawnpsdlgqmvlppchtmcq
fyvdngelscqlyqrsgdmglgvpfnlasygllthmiakvcglkpgtlvhtlgdahvysn
hvdalkiqldrepyafpkirftrdvasiddftsdmialddykchpkipmd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4irrB (B:)
mevmnkeniiadapsdvvktvqqqvhlnqdeykylkqveqilregtrrddrtgtgtisif
gmqskyclrngtipllttkrvywkgvleellwfisgstdgkllmeknvkiwekngdrafl
dnlgftsreegdlgpvygfqwrhfgakyvdchtdysgqgvdqlaevirqikeqpdsrrii
msawnpsdlgqmvlppchtmcqfyvdngelscqlyqrsgdmglgvpfnlasygllthmia
kvcglkpgtlvhtlgdahvysnhvdalkiqldrepyafpkirftrdvasiddftsdmial
ddykchpkipmdmav

    Sequence, based on observed residues (ATOM records): (download) 
    >4irrB (B:)
qqvhlnqdeykylkqveqilregtrrddrtgtgtisifgmqskyclrngtipllttkrvy
wkgvleellwfisgstdgkllmeknvkiwekngdrafldnlgftsreegdlgpvygfqwr
hfgakyvdchtdysgqgvdqlaevirqikeqpdsrriimsawnpsdlgqmvlppchtmcq
fyvdngelscqlyqrsgdmglgvpfnlasygllthmiakvcglkpgtlvhtlgdahvysn
hvdalkiqldrepyafpkirftrdvasiddftsdmialddykchpkipmd